HOXA1
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Official Full Name
homeobox A1 -
Overview
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region. [provided by RefSeq, Jul 2008] -
Synonyms
HOXA1;homeobox A1;BSAS;HOX1;HOX1F;homeobox protein Hox-A1;homeobox 1F;homeo box A1;lab-like protein;Hox 1.6-like protein;homeobox protein Hox-1F;HOX A1 homeodomain protein
Recombinant Proteins
- Human
- Rat
- Wheat Germ
- Mammalian Cell
- E.coli
- HEK293
- In Vitro Cell Free System
- Non
- His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HOXA1-28508TH | Recombinant Human HOXA1 | Wheat Germ | Human | Non | 109 amino acids |
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| HOXA1-2892R | Recombinant Rat HOXA1 Protein | Mammalian Cell | Rat | His |
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| HOXA1-4937H | Recombinant Human HOXA1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| HOXA1-6949H | Recombinant Human HOXA1 protein, His-tagged | E.coli | Human | His | Met1-His335 |
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| HOXA1-5430HCL | Recombinant Human HOXA1 293 Cell Lysate | HEK293 | Human | Non |
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| HOXA1-2547R | Recombinant Rat HOXA1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| HOXA1-2547R-B | Recombinant Rat HOXA1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| HOXA1-3705HF | Recombinant Full Length Human HOXA1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 335 amino acids |
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Involved Pathway
HOXA1 involved in several pathways and played different roles in them. We selected most pathways HOXA1 participated on our site, such as Neural Crest Differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with HOXA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neural Crest Differentiation | MIA,PRTG,CDH6,TFAP2B,DLL3,TBX6,OLIG3,TCF4,MBP,PHOX2B |
Protein Function
HOXA1 has several biochemical functions, for example, protein binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HOXA1 itself. We selected most functions HOXA1 had, and list some proteins which have the same functions with HOXA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | GSX1,RREB1,MYBBP1A,MSXD,NKX1.2LA,GSX2,FOXF1,DBPB,RARGA,PHOX2BB |
| protein binding | UROD,RNF149,RNASE1,HSF2,KIF1C,COL6A2,PDIA4,RFWD3,NUDT10,EIF4E2 |
Interacting Protein
HOXA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HOXA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HOXA1.
GRN;KRTAP4-12;PRNP;Hoxa1;TRIM42;80125
Resources
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References
- Liu, NM; Yokota, T; et al. Transcription Profiles of Endothelial Cells in the Rat Ductus Arteriosus during a Perinatal Period. PLOS ONE 8:-(2013).
- Zarif, MN; Soleimani, M; et al. Megakaryocytic differentiation of CD133+ hematopoietic stem cells by down-regulation of microRNA-10a. HEMATOLOGY 18:93-100(2013).
