GSTA1
-
Official Full Name
Glutathione S-transferase A1 -
Overview
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. -
Synonyms
Glutathione S alkyltransferase A1;Glutathione S aryltransferase A1;Glutathione S transferase 2;Glutathione S transferase A1;Glutathione S transferase alpha 1;Glutathione S transferase Ha subunit 1;Glutathione S-transferase A1;GST class-alpha member 1;GST epsilon;GST HA subunit 1;GST, class alpha, 1;GST-epsilon;GST2;GSTA1 1;GSTA1;GSTA1-1;GSTA1_HUMAN;GTH1;HA subunit 1;MGC131939;OTTHUMP00000016611;S (hydroxyalkyl)glutathione lyase A1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- E. coli
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
GSTA1 involved in several pathways and played different roles in them. We selected most pathways GSTA1 participated on our site, such as Glutathione metabolism,Metabolism of xenobiotics by cytochrome P,Drug metabolism - cytochrome P, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSTA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Drug metabolism - cytochrome P | AOX4,GSTM3,GSTP1,UGT1A7C,GSTT1,MGST3,GSTAL,GSTM1,ADH1,GSTO1 |
| Chemical carcinogenesis | UGT2A1,ADH5,CYP2C70,GSTO2,ADH4,UGT1A3,SULT1A2,CYP2C9,CYP2A6,CYP2A13 |
| Glutathione metabolism | PGD,LAP3,GSS,GGT6,ODC1,MGST3,GSTM4,GGT5,GGCT,OPLAH |
| Metabolism of xenobiotics by cytochrome P | UGT1A3,HSD11B1,MGST1,AKR7A3,GSTT2,GSTM7,GSTP2,GSTM3,GSTM4,UGT1A7 |
Protein Function
GSTA1 has several biochemical functions, for example, glutathione transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSTA1 itself. We selected most functions GSTA1 had, and list some proteins which have the same functions with GSTA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glutathione transferase activity | MGST3,GSTM4,GSTO2,HPGDS,GSTA5,GSTAL,GSTA2,GSTP1,GSTZ1,GSTT1B |
Interacting Protein
GSTA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSTA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GSTA1.
YWHAE;LSM3;PPP2CB;ST3GAL1;y5405_bacan;RPAIN
Resources
Related Services
Related Products
References
- Motts, JA; Shirley, DL; et al. Novel biomarkers of mercury-induced autoimmune dysfunction: A cross-sectional study in Amazonian Brazil. ENVIRONMENTAL RESEARCH 132:12-18(2014).
- Odenthal, J; van Heumen, BWH; et al. The Influence of Curcumin, Quercetin, and Eicosapentaenoic Acid on the Expression of Phase II Detoxification Enzymes in the Intestinal Cell Lines HT-29, Caco-2, HuTu 80, and LT97. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL 64:856-863(2012).
