GMPR
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Official Full Name
guanosine monophosphate reductase -
Overview
This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides. -
Synonyms
GMPR;guanosine monophosphate reductase;GMP reductase 1;GMPR1_HUMAN;Guanosine 5 monophosphate oxidoreductase 1;Guanosine 5-monophosphate oxidoreductase 1;Guanosine monophosphate reductase 1;guanine monophosphate reductase;GMPR1
Recombinant Proteins
- Human
- Rat
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- E. coli
- Mammalian cells
- Wheat Germ
- In Vitro Cell Free System
- His
- His&Fc
- Non
- Myc&DDK
- His&Fc&Avi
- His&SUMO
- GST
Involved Pathway
GMPR involved in several pathways and played different roles in them. We selected most pathways GMPR participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with GMPR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine metabolism | ATIC,NUDT16,PRPS1A,AMPD3,NT5C1A,NT5C3B,ENTPD6,PDE9A,UOX,POLR3G |
Protein Function
GMPR has several biochemical functions, for example, GMP reductase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GMPR itself. We selected most functions GMPR had, and list some proteins which have the same functions with GMPR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GMP reductase activity | GMPR2,TM9SF1 |
| metal ion binding | TDO2,PPM1BA,ZNF558,CYP2AD3,AOX4,DZIP1L,KDM6BB,TKTL1,FGD4A,IKZF4 |
Interacting Protein
GMPR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GMPR here. Most of them are supplied by our site. Hope this information will be useful for your research of GMPR.
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References
- Chen, JL; Zhang, ZG; et al. Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke. ANNALS OF NEUROLOGY 53:743-751(2003).
- Kallies, A; Gebauer, G; et al. Light effects on cyclic nucleotide levels and phase shifting of the circadian clock in Neurospora crassa. PHOTOCHEMISTRY AND PHOTOBIOLOGY 63:336-343(1996).
