FGL2
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Official Full Name
fibrinogen-like 2 -
Overview
The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. -
Synonyms
FGL2;fibrinogen-like 2;fibroleukin;pT49;T49;fibrinogen-like protein 2
Recombinant Proteins
- Human
- Rat
- Mouse
- Cynomolgus
- Rhesus macaque
- Zebrafish
- Chicken
- E.coli
- Mammalian Cell
- N-His-Avi,N-Flag
- N-hFc-Flag
- HEK293
- CHO
- Yeast
- Mammalian cells
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
- Flag
Involved Pathway
FGL2 involved in several pathways and played different roles in them. We selected most pathways FGL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with FGL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
FGL2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by FGL2 itself. We selected most functions FGL2 had, and list some proteins which have the same functions with FGL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
FGL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGL2.
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References
- Urbanellis, P; Shyu, W; et al. The regulatory T cell effector molecule fibrinogen-like protein 2 is necessary for the development of rapamycin-induced tolerance to fully MHC-mismatched murine cardiac allografts. IMMUNOLOGY 144:91-106(2015).
- Sun, Y; Xi, D; et al. Soluble FGL2, a novel effector molecule of activated hepatic stellate cells, regulates T-cell function in cirrhotic patients with hepatocellular carcinoma. HEPATOLOGY INTERNATIONAL 8:567-575(2014).
