FCER1G
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Official Full Name
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -
Overview
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. -
Synonyms
FCER1G;Fc fragment of IgE, high affinity I, receptor for;gamma polypeptide;high affinity immunoglobulin epsilon receptor subunit gamma;fcRgamma;fceRI gamma;fc-epsilon RI-gamma;Fc receptor gamma-chain;immunoglobulin E receptor, high affinity, gamma
Recombinant Proteins
- Human
- Chicken
- Mouse
- Zebrafish
- Rat
- Mus musculus
- E.coli
- Wheat Germ
- HEK293
- Mammalian Cell
- HEK293T
- Yeast
- Mamanlian cells
- In Vitro Cell Free System
- E.coli expression system
- GST
- Myc&DDK
- His
- Non
- His&B2M
- His&Fc&Avi
- Flag
Involved Pathway
FCER1G involved in several pathways and played different roles in them. We selected most pathways FCER1G participated on our site, such as Sphingolipid signaling pathway,Phospholipase D signaling pathway,Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCER1G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Phospholipase D signaling pathway | AVPR1B,INS,GAB2,PIK3R2,GRM3,PPAP2C,CXCR2,PLCB1,DGKD,AGTR1A |
| Fc epsilon RI signaling pathway | VAV2,BTK,GAB2,IL3,MAP2K4,RAF1,FYN,RAC3,MS4A2,PLA2G4D |
| Asthma | IL4,CD40,HLA-DMA,HLA-DQA2,IL13,HLA-DRB1,PRG2,MS4A2,IL9,HLA-DPB1 |
| Platelet activation | MAPK1,F2R,PRKACG,MAPK13,PIK3R2,NOS3,FYN,MAPK11,PIK3R1,AKT1 |
| Natural killer cell mediated cytotoxicity | PTPN6,TNFRSF10B,KLRC3,PIK3R3,IFNA2,SH2D1B,IFNG,KLRC2,SHC1,NCR3 |
| Tuberculosis | TGFB3,CASP9,IFNA1,EP300,CALM2,IL1B,LAMP1,CD209,PIK3C3,PPP3CA |
| Sphingolipid signaling pathway | PTEN,GNA12,RAF1,MAPK3,PLCB4,CERS4,KRAS,ROCK1,SGMS2,PPP2R1B |
Protein Function
FCER1G has several biochemical functions, for example, IgE binding,IgE receptor activity,IgG binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCER1G itself. We selected most functions FCER1G had, and list some proteins which have the same functions with FCER1G. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| IgE receptor activity | FCER1A,MS4A2,CD247L |
| IgG binding | FCGR1A,FCGR2A,FCGR3A,CD247L,FCGR1,FCGRT,FCGR2C,FCGR3B,UMOD,cgr2b |
| protein binding | FBXW11,NPY1R,MAP2K6,FBXL5,FCN1,WNT3A,MIIP,ZBTB32,ARHGAP26,NASP |
| IgE binding | CD247L,MS4A2,Fcer2a,LGALS3,FCER1A,FCER2 |
Interacting Protein
FCER1G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCER1G here. Most of them are supplied by our site. Hope this information will be useful for your research of FCER1G.
SYK;BTK;GP6;q81k29_bacan;q8cl35_yerpe
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