DLL3
-
Official Full Name
delta-like 3 (Drosophila) -
Overview
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] -
Synonyms
DLL3;delta-like 3 (Drosophila);SCDO1;delta-like protein 3;delta3;drosophila Delta homolog 3
Recombinant Proteins
- Human
- Cynomolgus
- Mouse
- Rat
- Rhesus macaque
- Mus musculus
- C-His-Avi
- HEK293
- E.coli
- Mammalian Cell
- Yeast
- CHO
- E.coli expression system
- His&Avi
- His
- C-lFc
- His&SUMO
- Fc
- FLAG
- His&Fc&Avi
- MBP&His&Avi
- His&Flag
Involved Pathway
DLL3 involved in several pathways and played different roles in them. We selected most pathways DLL3 participated on our site, such as Neural Crest Differentiation,Notch Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DLL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neural Crest Differentiation | SOX10,HEY2,ASCL1,CDH6,FOXD3,LHX1,TFAP2A,TCF4,SOX5,CTBP2 |
| Notch signaling pathway | RBPJA,NCSTN,MARK2,DLA,LFNG,ADAM17A,DTX2,PSENEN,HES1,MYCBP |
Protein Function
DLL3 has several biochemical functions, for example, Notch binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DLL3 itself. We selected most functions DLL3 had, and list some proteins which have the same functions with DLL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Notch binding | DTX1,DNER,JAG2,JAG1,JAG1B,NOV,NOTCH4,EGFL7,ADAM17,SNW1 |
Interacting Protein
DLL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DLL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DLL3.
Resources
Related Services
Related Products
References
