DKK3
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Official Full Name
dickkopf 3 homolog -
Overview
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. -
Synonyms
DKK3;dickkopf 3 homolog (Xenopus laevis);dickkopf (Xenopus laevis) homolog 3;dickkopf-related protein 3;regulated in glioma;REIC;RIG;dkk-3;hDkk-3;dickkopf-3;RIG-like 5-6;RIG-like 7-1;dickkopf homolog 3
Recombinant Proteins
- Mouse
- Human
- Rat
- Rhesus macaque
- Zebrafish
- Chicken
- HEK293
- E.coli
- CHO
- Mouse myeloma cell
- Mammalian Cells
- Wheat Germ
- Human Cells
- In Vitro Cell Free System
- His
- Non
- His&T7
- GST
- His&Avi
- His&Fc&Avi
- Myc&DDK
Involved Pathway
DKK3 involved in several pathways and played different roles in them. We selected most pathways DKK3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DKK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DKK3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by DKK3 itself. We selected most functions DKK3 had, and list some proteins which have the same functions with DKK3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
DKK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DKK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DKK3.
AURKA;PPM1D;BCAR3;ul31_ebvb9;CDH1;APC;SMAD4;ESR2;UBQLN4
Resources
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References
