DGAT2
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Official Full Name
diacylglycerol O-acyltransferase 2 -
Overview
Acyl-CoA:diacylglycerol acyltransferase, or DGAT (EC 2.3.1.20), is responsible for the synthesis of triglycerides. It catalyzes a reaction in which diacylglycerol is covalently joined to long chain fatty acyl-CoAs. -
Synonyms
DGAT2;diacylglycerol O-acyltransferase 2;diacylglycerol O acyltransferase homolog 2 (mouse);DGAT2_HUMAN;Diacylglycerol O acyltransferase like protein 2;Diacylglycerol O-acyltransferase homolog 2 (mouse);Diacylglycerol O-acyltransferase homolog 2;Diacylglycerol O-acyltransferase-like protein 2 isoform 1;Diglyceride acyltransferase 2;DKFZp686A15125;GS1999full;HMFN1045;diacylglycerol O-acyltransferase-like protein 2
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- Dictyostelium Discoideum
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Xenopus laevis
- Arabidopsis thaliana
- zebrafish
- Mus musculus
- Bovine
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli expression system
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
DGAT2 involved in several pathways and played different roles in them. We selected most pathways DGAT2 participated on our site, such as Glycerolipid metabolism,Metabolic pathways,Fat digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with DGAT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | APIP,ACOX1,ITPA,GALNT3,CYP2J2,CDS1,PPAP2CB,TKTL2,CDO1,PDHA2 |
| Glycerolipid metabolism | PPAP2C,DGKB,DGKA,DGAT1,AKR1B1,DGKG,LYCAT,LCLAT1,AGPAT1,GLA |
| Fat digestion and absorption | PPAP2B,MOGAT2,PNLIPRP2,ACAT2,PLA2G5,DGAT1,PNLIPRP1,PLA2G1B,PLA2G2E,APOB |
Protein Function
DGAT2 has several biochemical functions, for example, 2-acylglycerol O-acyltransferase activity,diacylglycerol O-acyltransferase activity,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DGAT2 itself. We selected most functions DGAT2 had, and list some proteins which have the same functions with DGAT2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| retinol O-fatty-acyltransferase activity | DGAT1 |
| protein homodimerization activity | NADKD1,Anks6,USF2,PRDX4,DST,APOA4,SLC16A1,PLCB1,RBM11,MYPOP |
| 2-acylglycerol O-acyltransferase activity | DGAT1,MOGAT1,MOGAT3 |
| diacylglycerol O-acyltransferase activity | MOGAT1,DGAT1A,DGAT1B,MOGAT3,DGAT1 |
Interacting Protein
DGAT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DGAT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DGAT2.
VCP;AMFR
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