DENR
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Official Full Name
density-regulated protein -
Overview
This gene encodes a protein whose expression was found to increase in cultured cells at high density but not during growth arrest. This gene was also shown to have increased expression in cells overexpressing HER-2/neu proto-oncogene. The protein contains an SUI1 domain. In budding yeast, SUI1 is a translation initiation factor that along with eIF-2 and the initiator tRNA-Met, directs the ribosome to the proper translation start site. Proteins similar to SUI have been found in mammals, insects, and plants. -
Synonyms
DENR;density-regulated protein;DRP;DRP1;SMAP 3;DENR_HUMAN;Density regulated protein;DRP1 protein;Protein DRP1;SMAP-3;SMAP3;Smooth muscle cell associated protein 3;Smooth muscle cell-associated protein 3;OTTHUMP00000239609;OTTHUMP00000239610;smooth muscle cell associated protein-3
Recombinant Proteins
- Human
- Chicken
- Mouse
- Zebrafish
- Wheat Germ
- E.coli
- Mammalian Cell
- Human
- HEK293
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DENR-2536H | Recombinant Human DENR Protein, GST-tagged | Wheat Germ | Human | GST |
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| DENR-28065TH | Recombinant Human DENR, His-tagged | E.coli | Human | His | Full L. 1-198 a.a. |
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| DENR-28066TH | Recombinant Human DENR, His-tagged | E.coli | Human | His | 198 amino acids |
|
| DENR-3544C | Recombinant Chicken DENR | Mammalian Cell | Chicken | His |
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| DENR-3643H | Recombinant Human DENR, His-tagged | Human | Human | His |
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| DENR-4516M | Recombinant Mouse DENR Protein | Mammalian Cell | Mouse | His |
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| DENR-800Z | Recombinant Zebrafish DENR | Mammalian Cell | Zebrafish | His |
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| DENR-6975HCL | Recombinant Human DENR 293 Cell Lysate | HEK293 | Human | Non |
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| DENR-2332M | Recombinant Mouse DENR Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DENR-2332M-B | Recombinant Mouse DENR Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| DENR-2466HF | Recombinant Full Length Human DENR Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 198 amino acids |
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| Denr-2526M | Recombinant Mouse Denr Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| DENR-2816H | Recombinant Human DENR protein, His-SUMO-tagged | E.coli | Human | His&SUMO | 2-198aa |
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| DENR-3927H | Recombinant Human DENR Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
DENR involved in several pathways and played different roles in them. We selected most pathways DENR participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DENR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DENR has several biochemical functions, for example, molecular_function,protein binding,translation initiation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DENR itself. We selected most functions DENR had, and list some proteins which have the same functions with DENR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RBM17,RAB37,HMGB4,ITGAM,CLIC5,WWP2,NFE2L2,GAPDHS,DNMT1,IGF2R |
| translation initiation factor activity | EIF3S10,EIF2B5,EIF4E2RS1,EIF5B,EIF3J,EIF3BA,EIF3E,EIF1,EIF4BB,EIF3HB |
| molecular_function | DAB1B,DCUN1D5,REEP6,TSNAXIP1,ASMTL,FHDC1,CIDEC,MAGEA4,TMEM97,TBC1D2B |
Interacting Protein
DENR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DENR here. Most of them are supplied by our site. Hope this information will be useful for your research of DENR.
UBC;MARCH5;MCTS1;NELFB;ACADVL
Resources
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References
- Chen, YJ; Shi, GY; et al. Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling. CANCER RESEARCH 64:7302-7310(2004).
- Xu, FP; Zhao, ZZJ; et al. Cell density regulates tyrosine phosphorylation and localization of focal adhesion kinase. EXPERIMENTAL CELL RESEARCH 262:49-58(2001).
