DDT
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Official Full Name
D-dopachrome tautomerase -
Overview
D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22. -
Synonyms
DDT;D-dopachrome tautomerase;D-dopachrome decarboxylase;D dopachrome decarboxylase;DDCT;D dopachrome tautomerase;DOPD_HUMAN;Phenylpyruvate tautomerase II;OTTHUMP00000198527;OTTHUMP00000198528
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Chicken
- Zebrafish
- Mouse
- Cynomolgus
- Canine
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- Yeast
- In Vitro Cell Free System
- E. coli
- Mamanlian cells
- GST
- His
- Myc&DDK
- Non
- His&Fc&Avi
- His&Myc
- N-His&C-V5
- Flag
Involved Pathway
DDT involved in several pathways and played different roles in them. We selected most pathways DDT participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DDT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
DDT has several biochemical functions, for example, D-dopachrome decarboxylase activity,dopachrome isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DDT itself. We selected most functions DDT had, and list some proteins which have the same functions with DDT. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| dopachrome isomerase activity | DCT,MIF |
Interacting Protein
DDT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DDT here. Most of them are supplied by our site. Hope this information will be useful for your research of DDT.
EIF1B;HLA-B;VHL;IKBKE;DSTYK;dsbD
Resources
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References
- Qi, DK; Atsina, K; et al. The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injury. JOURNAL OF CLINICAL INVESTIGATION 124:3540-3550(2014).
- Wang, C; Zhang, Q; et al. p,p'-DDE Induces Apoptosis through the Modulation of Tumor Necrosis Factor alpha in PC12 Cells. CHEMICAL RESEARCH IN TOXICOLOGY 27:507-513(2014).
