DAPK2
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Official Full Name
death-associated protein kinase 2 -
Overview
This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis.It uses multiple polyadenylation sites. -
Synonyms
DAPK2;death-associated protein kinase 2;DRP 1;MGC119312;DAP kinase 2;DAP-kinase-related protein 1 beta isoform;DRP1;DRP-1
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- Sf9 Insect Cell
- Mammalian Cell
- Insect Cell
- HEK293
- HEK293T
- E.coli
- GST
- Non
- His
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DAPK2-2339H | Recombinant Human DAPK2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DAPK2-26805TH | Recombinant Human DAPK2 | Human | Non | Full L. 1-370 a.a. |
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| DAPK2-290H | Recombinant Human DAPK2, GST-tagged, Active | Sf9 Insect Cell | Human | GST |
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| DAPK2-4305M | Recombinant Mouse DAPK2 Protein | Mammalian Cell | Mouse | His |
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| DAPK2-675H | Recombinant Human Death-Associated Protein Kinase 2, His-tagged | Insect Cell | Human | His | Full L. |
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| DAPK2-7076HCL | Recombinant Human DAPK2 293 Cell Lysate | HEK293 | Human | Non |
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| DAPK2-1237H | Recombinant Human DAPK2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| DAPK2-1311H | Recombinant Human DAPK2 Protein, His-tagged | E.coli | Human | His | Met1-Thr235 |
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| DAPK2-2201M | Recombinant Mouse DAPK2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| DAPK2-2201M-B | Recombinant Mouse DAPK2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Dapk2-2452M | Recombinant Mouse Dapk2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
DAPK2 involved in several pathways and played different roles in them. We selected most pathways DAPK2 participated on our site, such as Pathways in cancer,Bladder cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAPK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Bladder cancer | E2F2,ARAF,FGFR3,DAPK1,E2F1,RAF1,RPS6KA5,NRAS,MAPK3,MYC |
| Pathways in cancer | PTCH2,RAF1,KITLG,BDKRB1,PTCH1,FGF10,BAD,IKBKB,NTRK1,FZD9 |
Protein Function
DAPK2 has several biochemical functions, for example, ATP binding,calmodulin binding,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DAPK2 itself. We selected most functions DAPK2 had, and list some proteins which have the same functions with DAPK2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein serine/threonine kinase activity | PLK1,STK25,CDK12,NLK1,DYRK1B,AKT2L,TAF1,CIT,STRC,CDC42BPA |
| identical protein binding | CLDN9,KDM6A,USP4,Serpina1c,PARK7,EID3,SMAD6,HOOK2,CLDN4,SETX |
| protein binding | FAM9C,SPATA22,E2F2,PAX5,HAND2,UBLCP1,AP5S1,C1orf187,CDT1,FYTTD1 |
| calmodulin binding | TRPV5,GM101,TRPV1,PHKG2,CNN1A,CAMK2G,MAPKAPK2B,MKNK2,CAMKV,MYH1E |
| ATP binding | ATAD1A,CHEK2,DHX16,CUL9,UBE2G2,TTBK2,ACLY,ETNK2,VSIG8B,PCCB |
Interacting Protein
DAPK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAPK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DAPK2.
FAM9B;Bub1;LLGL2;KLC3;TUBGCP5;RACGAP1
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