Cd2
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Official Full Name
CD2 molecule -
Overview
CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it. -
Synonyms
CD2;CD2 molecule;CD2 antigen (p50), sheep red blood cell receptor , SRBC;T-cell surface antigen CD2;LFA-3 receptor;rosette receptor;erythrocyte receptor;lymphocyte-function antigen-2;T-cell surface antigen T11/Leu-5;CD2 antigen (p50), sheep red b
Recombinant Proteins
- Human
- Mouse
- Cynomolgus
- Rat
- Canine
- Rhesus macaque
- Bovine
- Horse
- Mus musculus
- E.coli
- HEK293
- Wheat Germ
- Mammalian Cell
- Human Cell
- E. coli
- HEK293T
- Mammalian cells
- Human Cells
- In Vitro Cell Free System
- Baculovirus
- HEK293F
- E.coli expression system
- GST
- His
- Fc
- His&Flag
- His&GST
- Non
- C-EGFP
- N-Twin strep and C-His&Flag
- Flag
- His&Fc&Avi
- His&SUMO
- His&Avi
- Myc&DDK
Involved Pathway
Cd2 involved in several pathways and played different roles in them. We selected most pathways Cd2 participated on our site, such as Cell adhesion molecules (CAMs),Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cd2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hematopoietic cell lineage | Flt3l,GM13305,IL7,IL1R1,CD3E,EPO,CD37,HLA-DRA,MS4A1,CD36 |
| Cell adhesion molecules (CAMs) | HLA-DMA,BLB1,GLG1,CD6,CNTNAP2,CLDNB,CLDN3,SDC4,MAG,ITGA9 |
Protein Function
Cd2 has several biochemical functions, for example, protein binding,protein homodimerization activity,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Cd2 itself. We selected most functions Cd2 had, and list some proteins which have the same functions with Cd2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | TESC,BOK,HSPB6,SMAD3,Defa-rs7,RXRB,PRDM6,DMRTA2,NR2C1,CTBP2A |
| receptor activity | NLGN4A,KIR2DL1,NRP2,NLGN2B,GFRA2A,GRIN2BB,ADCYAP1R1,TNFRSF6B,CRLF1,CADM2A |
| receptor binding | PDGFRB,PVRL2L,GLA,FGF13A,NRTN,DPP4,NTF3,CD200,NRXN1,WNT7AA |
| protein binding | S100A7,FBXO6,PTTG1IP,HBZ,CCNB1,MAU2,CHCHD1,AGL,DNAI1,RAB5C |
Interacting Protein
Cd2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cd2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cd2.
CD2BP2;CD2AP
Resources
Research Area
Natural Killer (NK) Cell CD AntigenT Cell Markers
CD Antigen (T Cell Migration/Adhesion)
Co-stimulatory Molecules
Lymphoid Lineage Markers
Dendritic Cell Co-stimulatory Molecules
MDSC Phenotyping - Positive Markers
Related Services
Related Products
References
- Hora, A; Shetty, VK; et al. Partial Purification and Characterization of Chromate Reductase of a Novel Ochrobactrum sp. Strain Cr-B4. PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY 45:769-784(2015).
- Zhao, YM; Zhang, ZP; et al. A Facile Synthesis Routine of Ag2S-CdS Heterostructure Nanorods with Enhanced Trap Emissions. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY 15:5087-5092(2015).
