CSNK2B
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Official Full Name
casein kinase 2, beta polypeptide -
Overview
Protein kinase CK2 or PKCK2 (formerly known as casein kinase 2) is a serine/threonine kinase, and consists of two constitutively active catalytic (alpha and alpha’) and two identical regulatory (beta) subunits that form an active tetrameric holozyme. CK2 -
Synonyms
CSNK2B;casein kinase 2, beta polypeptide;casein kinase II subunit beta;phosvitin;CK II beta;protein G5a;Casein kinase II beta subunit;alternative name: G5a, phosvitin;G5A;CK2B;CK2N;CSK2B;MGC138222;MGC138224
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- Chicken
- Zebrafish
- Wheat Germ
- E.coli
- Mammalian Cell
- HEK293
- Human Cells
- In Vitro Cell Free System
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
CSNK2B involved in several pathways and played different roles in them. We selected most pathways CSNK2B participated on our site, such as ALK1 signaling events,Adherens junction,Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with CSNK2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | HIST3H2BB,CCNB3,ORC2L,CLASP1A,TUBGCP5,YWHAE2,HAUS2,PLK1,TTK,DULLARD |
| Epstein-Barr virus infection | MAPK12,STAT3,PSMD12,PSMD11,PLCG1,CD44,NFKBIA,POLR2J3,POLR2A,CDK1 |
| Cell Cycle, Mitotic | NDEL1A,NUDC,CENPJ,SET,CDT1,CCDC99,TUBGCP4,CEP76,CDK4,SGOL1 |
| ALK1 signaling events | GDF2,FKBP1A,ACVRL1 |
| Condensation of Prometaphase Chromosomes | NCAPD2,SMC4,CSNK2A2,NCAPH,NCAPG,SMC2,CSNK2A1 |
| Adherens junction | CREBBP,RHOAC,MAPK3,ACTN2,RAC3,PTPRJ,SRC,LMO7,RHOAA,WASF3B |
| Developmental Biology | GDF1,CLTC,SCN2A,MED8,MED25,CACNG2,PEBP1,ACTR3,DUSP1,NRP1A |
| Axon guidance | EFNA3,IL17RD,GNAI2,WDR83,MAPK3,RGMA,FGF10B,RGMB,LIMK1,JAK3 |
Protein Function
CSNK2B has several biochemical functions, for example, chromatin binding,identical protein binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CSNK2B itself. We selected most functions CSNK2B had, and list some proteins which have the same functions with CSNK2B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase regulator activity | KIDINS220,CDK5RAP1,ANKRD54,KIDINS220B,RAC2,CDC37,APC,FAF1 |
| identical protein binding | SERPINB1A,RNF4,ADIPOR2,APPL1,SDK2,NEFL,PFKL,CLDN20,GRB2,DDX58 |
| transcription factor binding | THRA,PAX6,GCM1,NCOA2,SP1,BPTF,NBN,ID1,DNAJA3,RNF4 |
| chromatin binding | KLF6A,MBD5,MCM5,PBRM1L,KDM5A,JUB,MTA1,KLF14,JARID2,HDAC2 |
| protein binding | YEATS4,AMPD2,POLE3,PHLDA1,EHHADH,BFSP2,SREK1,BRAF,DCTN1,GATA1 |
| metal ion binding | GLIS3,PC,Car2,PKM,ZNF620,CYP2AA8,ZNF577,CLPX,PHF23A,BMPR1BA |
| protein domain specific binding | ERCC1,TADA3,PRKCZ,YWHAZ,ACSL3,MPP5,POU2F2,TNNI3,AKAP1,TWIST1 |
| receptor binding | RSPO1,SERPINE2,EDA,TAC4,F2R,GNB2L1,FGF11,NCK1,PANX1,ECH1 |
Interacting Protein
CSNK2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CSNK2B here. Most of them are supplied by our site. Hope this information will be useful for your research of CSNK2B.
CSNK2A1;CSNK2A2
CSNK2B Related Signal Pathway
Resources
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References
- Casas, B; Calabokis, M; et al. Trypanosoma cruzi: in vitro phosphorylation of tubulin by a protein kinase CK2-like enzyme. EXPERIMENTAL PARASITOLOGY 101:129-137(2002).
- Mercado, L; Itarte, E; et al. Immunological detection of a CK2 activity in Tapes semidecussatus (Mollusca, Bivalvia) mantle. MALACOLOGIA 43:217-222(2001).
