COL8A1

  • Official Full Name

    collagen, type VIII, alpha 1

  • Overview

    This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same isoform have been observed.

  • Synonyms

    COL8A1;collagen, type VIII, alpha 1;C3orf7, chromosome 3 open reading frame 7;collagen alpha-1(VIII) chain;MGC9568;C3orf7;CO8A1_HUMAN;Collagen alpha 1(VIII) chain [Precursor];Endothelial collagen;Vastatin;OTTHUMP00000192896;OTTHUMP00000192897;collagen VIII, alpha-1 polypeptide;cell proliferation-inducing protein 41;smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • Rat
  • Rabbit
  • E.coli
  • Mammalian Cells
  • HEK293
  • Yeast
  • His
  • Non
  • His&Fc&Avi
  • His&SUMO
Cat.# Product name Source (Host) Species Tag Protein Length Price
COL8A1-11440H Recombinant Human COL8A1, His-tagged E.coli Human His 396-744a.a.
COL8A1-140H Recombinant Human COL8A1, His-tagged E.coli Human His Pro575~Pro743
COL8A1-3752M Recombinant Mouse COL8A1 Protein Mammalian Cells Mouse His
COL8A1-5533C Recombinant Chicken COL8A1 Mammalian Cells Chicken His
COL8A1-7376HCL Recombinant Human COL8A1 293 Cell Lysate HEK293 Human Non
COL8A1-1770H Recombinant Human COL8A1 Protein (Gly28-Met744), C-His tagged Mammalian Cells Human His Gly28-Met744
COL8A1-1873M Recombinant Mouse COL8A1 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
COL8A1-1873M-B Recombinant Mouse COL8A1 Protein Pre-coupled Magnetic Beads HEK293 Mouse
Col8a1-338M Recombinant Mouse Col8a1 Protein, His-tagged E.coli Mouse His Glu583~Pro743
Col8a1-339R Recombinant Rat Col8a1 Protein, His-tagged E.coli Rat His Leu590~Met744
COL8A1-4534H Recombinant Human COL8A1 protein, His-SUMO-tagged E.coli Human His&SUMO 572-744aa
COL8A1-5633H Recombinant Human COL8A1 protein, His-tagged Yeast Human His 572-744aa
COL8A1-823R Recombinant Rabbit COL8A1 Protein, His-tagged E.coli Rabbit His Leu590-Met744

    Involved Pathway

    COL8A1 involved in several pathways and played different roles in them. We selected most pathways COL8A1 participated on our site, such as Assembly of collagen fibrils and other multimeric structures,Collagen biosynthesis and modifying enzymes,Collagen formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL8A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Collagen biosynthesis and modifying enzymes COL4A3,COL8A1A,COL9A1A,PCOLCE,COL28A1D,PCOLCE2,TLL1,COL4A5,COL19A1,PPIB
    Assembly of collagen fibrils and other multimeric structures COL4A4,TLL1,COL8A2,COL4A5,BMP1B,LOXL4,COL6A1,PLEC,LOXL3,CTSL2
    Extracellular matrix organization F11R.2,COL9A1A,MMP19,MFAP1,FURINA,LEPREL1,LTBP4,COL17A1,ICAM4,P3H2
    Collagen formation CRTAP,TLL1,BMP1,COL28A1,MMP13,EMID2,COL11A1B,COL9A1B,COL9A1A,COL28A1A

    Protein Function

    COL8A1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL8A1 itself. We selected most functions COL8A1 had, and list some proteins which have the same functions with COL8A1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding BLOC1S1,CBLN3,LTBP1,ELMOD3,EYA1,LOXL3,NELL2,GLMN,IL33,MAGEF1

    Interacting Protein

    COL8A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL8A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL8A1.

    KRTAP26-1;KRTAP10-7;KRTAP10-8;SP4;CREB5;REL

    Resources

    Research Area

    Collagens

    References

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