CDC34

  • Official Full Name

    cell division cycle 34 homolog

  • Overview

    Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first

  • Synonyms

    CDC34;cell division cycle 34 homolog (S. cerevisiae);cell division cycle 34;ubiquitin-conjugating enzyme E2 R1;E2 CDC34;UBC3;UBE2R1;ubiquitin carrier protein;ubiquitin-protein ligase R1;ubiquitin-conjugating enzyme E2-CDC34;ubiquitin-conjugating

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Wheat Germ
  • HEK293
  • Insect Cell
  • HEK293T
  • In Vitro Cell Free System
  • GST
  • His
  • Non
  • His&Strep
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
CDC34-11005H Recombinant Human CDC34, GST-tagged E.coli Human GST 1-236a.a.
CDC34-0929H Recombinant Human CDC34 Protein, GST-Tagged Wheat Germ Human GST
CDC34-138H Recombinant Human CDC34, His-tagged E.coli Human His
CDC34-224H Recombinant Human CDC34, His-tagged E.coli Human His Full L.
CDC34-26221TH Recombinant Human CDC34, His-tagged E.coli Human His Full L.
CDC34-26224TH Recombinant Human CDC34, His-tagged E.coli Human His 236 amino acids
CDC34-791H Recombinant Human CDC34, His-tagged E.coli Human His
CDC34-7660HCL Recombinant Human CDC34 293 Cell Lysate HEK293 Human Non
CDC34-0036H Recombinant Human CDC34 Protein (A2-S236), Tag Free Insect Cell Human Non A2-S236
CDC34-0037H Recombinant Human CDC34 Protein (A2-S236), His/Strep tagged Insect Cell Human His&Strep A2-S236
CDC34-1517H Recombinant Human CDC34 Protein (Met1-Ser236), N-His tagged E.coli Human His Met1-Ser236
Cdc34-2074M Recombinant Mouse Cdc34 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
CDC34-220H Recombinant Human CDC34 protein E.coli Human Non 236
CDC34-3072HF Recombinant Full Length Human CDC34 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 236 amino acids

    Involved Pathway

    CDC34 involved in several pathways and played different roles in them. We selected most pathways CDC34 participated on our site, such as Ubiquitin mediated proteolysis,Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC34 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Herpes simplex infection EEF1DA,MAPK10,Casp3,TAF5,TP53,NFKB1,SRSF2B,FB06F03,HLA-DMA,CUL1A
    Ubiquitin mediated proteolysis UBE3A,HERC3,NHLRC1,UBE2B,FLJ11011L,UBE2D2,UBE2N,RBX1,ITCH,UBE2M

    Protein Function

    CDC34 has several biochemical functions, for example, ATP binding,protein binding,ubiquitin conjugating enzyme activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC34 itself. We selected most functions CDC34 had, and list some proteins which have the same functions with CDC34. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ABCG2A,PRKCD,RAF1A,PKDCC,CLPB,FLT4,ATAD1,GRK7A,DDX56,BMPR1AA
    ubiquitin-protein transferase activity TOPORS,RNF6,UBE2R2,KLHL20,BIRC2,MUL1B,HECTD3,BIRC5A,TRIM5,TRIM9
    ubiquitin conjugating enzyme activity UBE2G1,UBE2Z,UBE2L3,UBE2D2,UBE2N,UBE2B,UBE2H,UBE2C,UBE2Q2,UBE2E2
    protein binding ECT2,DUSP1,DENND2D,RHOBTB3,STK10,RAP2B,PFDN2,SRSF10,SPHK2,TEX14
    ubiquitin protein ligase activity NHLRC1,CDC34B,CCNC,UBE2R2,RAD18,RNF139,ANKIB1,TRIM71,RNF2,CDK8
    ubiquitin protein ligase binding GPI1,RELA,CHEK2,JAK1,MAGEC2,SMAD3,HSPA1A,GABARAPL2,HSPA1L,MID1

    Interacting Protein

    CDC34 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC34 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC34.

    BTRC;CSNK2B;SDCBP;SIAH1;CUL1;ZNRF1;DUSP1;PPP1CC;CORO7;PPP1CB

    Resources

    Research Area

    E2 Ubiquitin/Ubl Conjugating Enzymes
    Ubiquitin-Proteasome Pathway

    References

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