CDC26
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Official Full Name
cell division cycle 26 homolog -
Overview
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc26, a component of cell cycle;anaphase-promoting complex (APC). APC is composed of a group of highly conserved proteins and functions as a cell;cycle-regulated ubiquitin-protein ligase. APC thus is responsible for the cell cycle regulated proteolysis of various;proteins. -
Synonyms
CDC26;cell division cycle 26 homolog (S. cerevisiae);C9orf17, cell division cycle 26 , chromosome 9 open reading frame 17;anaphase-promoting complex subunit CDC26;ANAPC12;anaphase promoting complex subunit 12;APC12;CDC26 subunit of anaphase promo
Recombinant Proteins
- Zebrafish
- Rat
- Human
- Chicken
- Rhesus macaque
- Mouse
- Mammalian Cells
- Human
- E.coli
- HEK293
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
CDC26 involved in several pathways and played different roles in them. We selected most pathways CDC26 participated on our site, such as Cell cycle,Oocyte meiosis,Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDC26 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Progesterone-mediated oocyte maturation | RPS6KAL,MAPK8A,HSP90AA1,ADCY2B,INS1,PIK3R3A,CDC25A,RPS6KA3,PIK3R3,MAPK10 |
| Ubiquitin mediated proteolysis | KLHL9,KLHL13,CUL1A,UBE1Y1,ANAPC13,BIRC3,RNF7,FBXW7,CDC27,UBE2E1 |
| HTLV-I infection | NFATC3,HLA-DRB5,HLA-DPA1,WNT2B,PRKACG,HLA-DQB1,CDC20,WNT6,ANAPC11,PIK3R1 |
| Cell cycle | SGOL2,CDH1-A,ANAPC1,CDKN2B,ENSAB,CDKN1B,SUN1,ORC4,ORC2L,ANAPC5 |
| Oocyte meiosis | CPEB3,YWHAG1,CDK1,REC8B,PPP3CA,CTH1,CPEB2,PTTG2,FBXW11,IGF1RB |
Protein Function
CDC26 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDC26 itself. We selected most functions CDC26 had, and list some proteins which have the same functions with CDC26. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ZNF239,MAP4K2,NAP1L4,P4HB,ARHGEF10,CHST13,HSPH1,TIPRL,IFT122,HM13 |
Interacting Protein
CDC26 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDC26 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDC26.
CDC16;Cdc23;Cdc16;Cdc20;Bub1b
Resources
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References
- Das, S; Basu, H; et al. Arrest of Nuclear Division in Plasmodium through Blockage of Erythrocyte Surface Exposed Ribosomal Protein P2. PLOS PATHOGENS 8:-(2012).
- Dorai, H; Li, K; et al. Genome-wide analysis of mouse myeloma cell lines expressing therapeutic antibodies. BIOTECHNOLOGY PROGRESS 23:911-920(2007).
