CD93
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Official Full Name
CD93 molecule -
Overview
The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally;identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now;is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular;cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking;transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. -
Synonyms
CD93;CD93 molecule;C1QR1, CD93 antigen , complement component 1, q subcomponent, receptor 1 , matrix remodelling associated 4 , MXRA4;complement component C1q receptor;C1qR(P);C1qRP;CDw93;dJ737E23.1;ECSM3;C1qR;CD93 antigen;C1q receptor 1;C1q/MBL/SPA receptor;matrix-remodelling associated 4;matrix-remodeling-associated protein 4;complement component 1 q subcomponent receptor 1;complement component 1, q subcomponent, receptor 1;C1QR1;MXRA4
Recombinant Proteins
- Human
- Mouse
- Cynomolgus
- Rat
- Chicken
- Mus musculus
- E.coli
- Mammalian cells
- HEK293
- Wheat Germ
- Mammalian Cell
- Insect Cell
- Human Cell
- Human cells
- HEK293T
- E.coli expression system
- His
- Fc
- GST
- His&Fc
- His&GST
- His&T7
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
- His&Avi
Involved Pathway
CD93 involved in several pathways and played different roles in them. We selected most pathways CD93 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CD93 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
CD93 has several biochemical functions, for example, calcium ion binding,carbohydrate binding,complement component C1q binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD93 itself. We selected most functions CD93 had, and list some proteins which have the same functions with CD93. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| complement component C1q binding | C4A,CALR,APCS,CRP,PTX3,C1QBP |
| receptor activity | PAQR5B,SMAGP,AGER,RET,ICAM1,VAC14,AMFR,BTN1A1,CD160,PLXNA1 |
| calcium ion binding | TESC,CALR,CCDC48,PCDHGA12,VLDLR,DGKAA,MMP20,MICU2,ACTN1,DSC2 |
| carbohydrate binding | Fcer2a,CNTN2,GANC,ACAN,Reg2,FREM1,CLEC6A,GFPT2,MBL1,GALNT7 |
| protein binding | ATP10A,PAX6,GLRB,PTGES3,SNX31,GZMM,SUPT6H,NUP155,MYLK,CDC26 |
Interacting Protein
CD93 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD93 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD93.
p27958-pro_0000037566;CRK;BAG6;COPS5;FAM46A;MYD88;UBQLN2;BAG4
Resources
Research Area
Endothelial Cell MarkersImmune Regulatory Molecules on Endothelial Cells
CD Antigen (Hematopoietic Stem Cell Markers)
Granulocyte Markers
Hematopoietic Stem Cell Markers
CD Antigen (Granulocyte Markers)
Monocyte Markers
C-type Lectin Receptors
Dendritic Cell Pathogen Recognition/Uptake
C-type Lectin Family
Related Services
Related Products
References
- Pedersen, GK; Adori, M; et al. B-1a transitional cells are phenotypically distinct and are lacking in mice deficient in I kappa BNS. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:E4119-E4126(2014).
- von Kietzell, K; Pozzuto, T; et al. Antibody-Mediated Enhancement of Parvovirus B19 Uptake into Endothelial Cells Mediated by a Receptor for Complement Factor C1q. JOURNAL OF VIROLOGY 88:8102-8115(2014).
