CADM1
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Official Full Name
cell adhesion molecule 1 -
Overview
Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene. -
Synonyms
CADM1;cell adhesion molecule 1;IGSF4, immunoglobulin superfamily, member 4 , TSLC1, tumor suppressor in lung cancer 1;BL2;IGSF4A;Necl 2;NECL2;nectin like 2;RA175;ST17;SYNCAM;SYNCAM1;CADM1_HUMAN;DKFZp686F1789;IgSF4;Immunoglobulin superfamily member 4;MGC149785;MGC51880;NECL-2;Nectin-like protein 2;SgIGSF;Spermatogenic immunoglobulin superfamily;sTSLC 1;Synaptic cell adhesion molecule;TSLC-1;TSLC1;Tumor suppressor in lung cancer 1;nectin-like 2;TSLC1/Nectin-like 2/IGSF4;immunoglobulin superfamily, member 4;immunoglobulin superfamily, member 4D variant 2;sTSLC-1
Recombinant Proteins
- Human
- Mouse
- HEK293
- E.coli
- Mammalian cells
- Human Cell
- Wheat Germ
- Mammalian Cell
- HEK293T
- His
- GST
- Fc
- His&GST
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
CADM1 involved in several pathways and played different roles in them. We selected most pathways CADM1 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with CADM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell adhesion molecules (CAMs) | L1CAM,ITGB7,NFASC,NTNG1,NLGN4A,TIGIT,CD34,NLGN2,HLA-DRB4,PVRL1B |
Protein Function
CADM1 has several biochemical functions, for example, PDZ domain binding,cell adhesion molecule binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CADM1 itself. We selected most functions CADM1 had, and list some proteins which have the same functions with CADM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor binding | DAO,APOL2,HFE2,CTNND1,C5,CAPRIN2,ADAM10,CXADR,C1QTNF2,CCL15 |
| receptor activity | GRIN1A,NRXN1,TLR2,PVR,CMKLR1,MED1,KLRB1B,PVRL1B,CD200R2,ADCYAP1R1 |
| protein binding | CLIC3,AHSA1,IFIH1,SSBP3,GPM6A,TAS2R16,ADAP1,STAP1,CASQ2,IL5RA |
| protein homodimerization activity | PEX11A,MID1,ODZ4,OXCT1,TARS,RIPK2,CADM3,SUMF1,MAP3K11,DMRTA2 |
| cell adhesion molecule binding | CXADR,CD226,NLGN4X,DSG2,PVRL4,CAML,NRXN3,NPTN,NLGN3,SDCBP |
| PDZ domain binding | ATP2B2,SLC22A5,EXOC4,CFTR,FZD7,SDC2,GJA1,ERC1,PLEKHA2,TBC1D10A |
Interacting Protein
CADM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CADM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CADM1.
PSMA6;ATF7IP;LIN7A;EPB41L3;ITGB4
Resources
Research Area
Immunoglobulin Superfamily CAMsIGSF4/SynCAM Family
Synaptic Adhesion Molecules
Dendritic Cell Adhesion and Migration
Related Services
Related Products
References
- Moiseeva, EP; Straatman, KR; et al. CADM1 Controls Actin Cytoskeleton Assembly and Regulates Extracellular Matrix Adhesion in Human Mast Cells. PLOS ONE 9:-(2014).
- Fossum, E; Grodeland, G; et al. Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8(+) T-cell responses against influenza virus. EUROPEAN JOURNAL OF IMMUNOLOGY 45:624-635(2015).
