CA12
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Official Full Name
carbonic anhydrase XII -
Overview
Carbonic anhydrases (CA) are a family of ancient zinc metalloenzymes found in almost all living organisms. All CA can be divided into 3 distinct classes (alpha, beta, and gamma) that evolved independently and have no significant homology in sequence and o -
Synonyms
CA12;carbonic anhydrase XII;carbonic anhydrase 12;HsT18816;CA-XII;carbonic dehydratase;carbonate dehydratase XII;tumor antigen HOM-RCC-3.1.3;CAXII;FLJ20151;CAR12;carbonic anyhydrase 12;CA XII;AI314958;2310047E01Rik
Recombinant Proteins
- Human
- Mouse
- Cynomolgus
- Rhesus macaque
- Rat
- E.coli
- HEK293
- Mammalian Cells
- C-His
- Wheat Germ
- Insect Cells
- Human Cells
- In Vitro Cell Free System
- Yeast
- Mouse
- GST
- His
- His&Avi
- Non
- His&Fc&Avi
- Myc&DDK
- Flag
- His&SUMO
Involved Pathway
CA12 involved in several pathways and played different roles in them. We selected most pathways CA12 participated on our site, such as Nitrogen metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CA12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Nitrogen metabolism | CA2,CAR6,GLULA,GLUD2,CA5B,CA4,Car12,CA1,CA5,CA9 |
Protein Function
CA12 has several biochemical functions, for example, carbonate dehydratase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CA12 itself. We selected most functions CA12 had, and list some proteins which have the same functions with CA12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | GRIN2B,CA5,PIAS1,TCEA3,SOD3A,FBXO11A,WBP7,UNKL,MIB1,MME |
| carbonate dehydratase activity | CAHZ,CA4A,CA15C,CAR13,CA8,CA9,CA4,CA13,Car9,Car2 |
Interacting Protein
CA12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CA12 here. Most of them are supplied by our site. Hope this information will be useful for your research of CA12.
SGSM2;ATP5C1;CUX1;LGALS7B;MAPK6;RDH11;TOE1;MRPL9;KATNBL1;DAXX
Resources
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References
- Pogue-Geile, KL; Kim, C; et al. Predicting Degree of Benefit From Adjuvant Trastuzumab in NSABP Trial B-31. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE 105:1782-1788(2013).
- Wilbur, DS; Chyan, MK; et al. Reagents for Astatination of Biomolecules. 6. An Intact Antibody Conjugated with a Maleimido-closo-Decaborate(2-) Reagent via Sulfhydryl Groups Had Considerably Higher Kidney Concentrations than the Same Antibody Conjugated with an Isothiocyanato-closo-Decaborate(2-) Reagent via Lysine Amines. BIOCONJUGATE CHEMISTRY 23:409-420(2012).
