BRK1
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Official Full Name
BRICK1, SCAR/WAVE actin-nucleating complex subunit -
Overview
C3orf10 is involved in regulation of actin and microtubule organization and is part of a WAVE complex that activates the Arp2/3 complex. -
Synonyms
BRK1;BRICK1, SCAR/WAVE actin-nucleating complex subunit;MDS027;hHBrk1;C3orf10;HSPC300
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| BRK1-416H | Recombinant Human BRICK1, SCAR/WAVE actin-nucleating complex subunit, His-tagged | E.coli | Human | His | 1-75 a.a. |
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| BRK1-5017H | Recombinant Human BRK1, His-tagged | E.coli | Human | His |
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| BRK1-8055HCL | Recombinant Human C3orf10 293 Cell Lysate | HEK293 | Human | Non |
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| BRK1-1039H | Recombinant Human BRK1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Brk1-178M | Recombinant Mouse Brk1 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
BRK1 involved in several pathways and played different roles in them. We selected most pathways BRK1 participated on our site, such as Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Actin Cytoskeleton | VIL1,PIK3R5,ARHGAP35,ARHGEF12,ARHGEF6,GNG12A,EZR,ITGAE,PDGFAB,RAC3A |
Protein Function
BRK1 has several biochemical functions, for example, contributes_to Rac GTPase binding,protein binding,protein complex binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRK1 itself. We selected most functions BRK1 had, and list some proteins which have the same functions with BRK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SGSM3,VAC14,CXCL9,GRAMD3,HSF2,SNAP91,MPL,CRB1,SCO2,NFKB1 |
| contributes_to Rac GTPase binding | ABI2,WASF1,CYFIP1,NCKAP1 |
| protein complex binding | PPFIA2,MAPK8IP2,CCND1,ST13,TRADD,SREBF1,LAMB3,RELA,RPTOR,KIF11 |
Interacting Protein
BRK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRK1.
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References
- Paganelli, L; Caillaud, MC; et al. Three BUB1 and BUBR1/MAD3-related spindle assembly checkpoint proteins are required for accurate mitosis in Arabidopsis. NEW PHYTOLOGIST 205:202-215(2015).
- Beike, AK; von Stackelberg, M; et al. Molecular evidence for convergent evolution and allopolyploid speciation within the Physcomitrium-Physcomitrella species complex. BMC EVOLUTIONARY BIOLOGY 14:-(2014).
