BRD2
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Official Full Name
bromodomain containing 2 -
Overview
Brd2 is a highly conserved member of the BET subfamily of bromodomain proteins that contain two tandem N-terminal bromodomains and a single C-terminal extra-terminal (ET) domain (1). In addition to its involvement in guiding the expression of cell cycle g -
Synonyms
BRD2;bromodomain containing 2;bromodomain-containing protein 2;D6S113E;FSRG1;KIAA9001;NAT;RING3;O27.1.1;bromodomain-containing 2;really interesting new gene 3 protein;female sterile homeotic-related gene 1;FSH;RNF3;FLJ31942;DKFZp686N0336
Recombinant Proteins
- Human
- Rat
- Chicken
- Wheat Germ
- E.coli
- E. coli
- Mammalian Cell
- In Vitro Cell Free System
- HEK293
- GST
- His&Flag
- His
- N-His&C-FLAG
- Non
- His&Fc&Avi
Involved Pathway
BRD2 involved in several pathways and played different roles in them. We selected most pathways BRD2 participated on our site, such as Regulation of retinoblastoma protein, which may be useful for your reference. Also, other proteins which involved in the same pathway with BRD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of retinoblastoma protein | GSC,AATF,CBX4,ATF7,BGLAP,MYOD1,SMARCB1,CKM,ELF1 |
Protein Function
BRD2 has several biochemical functions, for example, chromatin binding,lysine-acetylated histone binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BRD2 itself. We selected most functions BRD2 had, and list some proteins which have the same functions with BRD2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chromatin binding | SSBP1,GATA1A,MEIS3,POLG,YBX1,APBB1,TAF2,SOD3,ORC1L,LDB1 |
| lysine-acetylated histone binding | BRD9,TAF1,ATAD2B,BRD3,BAZ2A,PHIP,TRIM24,BAZ1B,CARM1,MLL1 |
| protein binding | TXLNA,DUSP14,IFI35,EIF4EBP1,NCL,CTH,ANKS4B,SKIL,PTH2R,PGBD1 |
Interacting Protein
BRD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BRD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BRD2.
RUNX3;HIST2H4B;CSNK2A2;mutT7;POLR2B;CSNK2A1;myc_human_gene;IL7R
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