AMY2B
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Official Full Name
amylase, alpha 2B (pancreatic) -
Overview
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and;thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several;amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase;isoenzyme produced by the pancreas. -
Synonyms
AMY2B;amylase, alpha 2B (pancreatic);AMY2, amylase, alpha 2B;pancreatic;alpha-amylase 2B;1;1,4-alpha-D-glucan glucanohydrolase;1,4-alpha-D-glucan glucanohydrolase 2B;4-alpha-D-glucan glucanohydrolase 2B;Alpha-amylase carcinoid;AMY2;AMY2B_HUMAN;amylase, alpha 2B;Amylase, pancreatic, alpha-2B;Carcinoid alpha-amylase;EC 3.2.1.1;Glycogenase;OTTHUMP00000012696
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- HEK293
- Wheat Germ
- Mammalian cells
- In Vitro Cell Free System
- Human Pancreas
- His
- GST
- Non
- His&Fc&Avi
- Fc
Involved Pathway
AMY2B involved in several pathways and played different roles in them. We selected most pathways AMY2B participated on our site, such as Starch and sucrose metabolism,Metabolic pathways,Pancreatic secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMY2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pancreatic secretion | CCKAR,RAP1A,ATP1B2,RAC1,CPB1,PLA2G12B,ATP1B4,ATP2A3,PRKCG,PLA2G2F |
| Carbohydrate digestion and absorption | PIK3R5,AMY2A3,HK1,AMY2A,SLC37A4,AMY1B,ATP1A4,ATP1A1,TAS1R2,PIK3R3 |
| Starch and sucrose metabolism | GBA3,UXS1,ENPP1,GPIB,UGT1A9,AMY2A3,UGT1A1,HK2,AMY1A,UGT1A6 |
| Metabolic pathways | ENO2,POLE2,AKR1B1L,CES1D,TDO2B,GGPS1,GALCA,ALDH6A1,OAT,HOGA1 |
Protein Function
AMY2B has several biochemical functions, for example, alpha-amylase activity,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMY2B itself. We selected most functions AMY2B had, and list some proteins which have the same functions with AMY2B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | RC3H2,WTIP,ZNF548,ELAC1,ZNF625,ZNF624,Adcy4,RREB1,OVOL2,ALPL |
| alpha-amylase activity | Amy1,AMY2A2,AMY2A4,AMY1A,AMY2A,AMY1B,AMY2A5,AMY2A3 |
Interacting Protein
AMY2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMY2B here. Most of them are supplied by our site. Hope this information will be useful for your research of AMY2B.
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References
- OMICHI, K; HASE, S; et al. DETECTION OF HUMAN URINARY ALPHA-AMYLASE ENCODED BY THE AMY2B GENE USING A FLUOROGENIC SUBSTRATE, FG5P. JOURNAL OF BIOCHEMISTRY 112:303-305(1992).
