AMY1A
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Official Full Name
amylase, alpha 1A (salivary) -
Overview
Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. Alternative splicing results in multiple transcript variants encoding the same protein. -
Synonyms
AMY1A;amylase, alpha 1A (salivary);AMY1, amylase, alpha 1A;salivary;alpha-amylase 1;glycogenase;salivary alpha-amylase;salivary amylase alpha 1A;amylase, salivary, alpha-1A;1,4-alpha-D-glucan glucanohydrolase 1;AMY1;AMY1B;AMY1C
Recombinant Proteins
- Chicken
- Human
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- Human Saliva
- His
- GST
- Myc&DDK
- His&Fc&Avi
- Non
- Flag
Involved Pathway
AMY1A involved in several pathways and played different roles in them. We selected most pathways AMY1A participated on our site, such as Starch and sucrose metabolism,Metabolic pathways,Salivary secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMY1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Carbohydrate digestion and absorption | AMY2A5,PIK3CB,ATP1B2,G6PC2,PIK3R1,FXYD2,ATP1B3,AMY2A3,SLC2A5,PIK3R5 |
| Salivary secretion | Adcy4,LYZ,BST1,DMBT1,PRKCB,PRH1,MUC7,FXYD2,TRPV6,CALM1 |
| Metabolic pathways | LDHAL6B,NT5C2A,MTMR3,TK1,HPSE,NNT,ALDH9A1B,ALP3,UGP2B,IDS |
| Starch and sucrose metabolism | UGDH,GYS2,UGP2B,GBE1,UGT2A2,PGM2,GAA,UGT1AB,HK1,UXS1 |
Protein Function
AMY1A has several biochemical functions, for example, alpha-amylase activity,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMY1A itself. We selected most functions AMY1A had, and list some proteins which have the same functions with AMY1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | HBZ,CALU,RBMY1A1,TSPAN12,TTC23L,HINFP,BAG3,FIGNL1,NUP85,CST9L |
| metal ion binding | ZNF512,PDE2A,ZNF354A,CNOT7,NR5A1A,ZNF692,POLB,RFWD2,IREB2,ZNF423 |
| alpha-amylase activity | AMY2A,AMY2B,AMY2A2,AMY1B,Amy1,AMY2A5,AMY2A3,AMY2A4 |
Interacting Protein
AMY1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMY1A here. Most of them are supplied by our site. Hope this information will be useful for your research of AMY1A.
MUC7;CDK2AP1;SOD2;RASSF6
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