AMH
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Official Full Name
anti-Mullerian hormone -
Overview
Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. -
Synonyms
AMH;anti-Mullerian hormone;muellerian-inhibiting factor;MIS;Anti muellerian hormone;MIF;Muellerian inhibiting factor;Mullerian inhibiting substance;anti-Muellerian hormone;Mullerian inhibiting factor;muellerian-inhibiting substance
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Chicken
- Mouse
- Pig
- Bovine
- E.coli
- E. coli
- Mammalian Cell
- HEK293
- HEK293 cells
- Mammalian cells
- HEK293T
- Insect Cell
- Yeast
- Mamanlian cells
- GST
- N-His
- Non
- His
- His&Flag
- Myc&DDK
- Fc
- His&Fc&Avi
- Flag
Involved Pathway
AMH involved in several pathways and played different roles in them. We selected most pathways AMH participated on our site, such as cAMP signaling pathway,Cytokine-cytokine receptor interaction,TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with AMH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | Ifna11,CCL27B,IFNAR2,IFNGR1,IL22RA2,IL13,KDRL,PDGFB,TNFSF9,PRLR |
| TGF-beta signaling pathway | BMPR1BB,GDF5,RPS6KB2,SMAD2,BMPR1AA,IFNG,BMPR2A,BAMBI,RBL1,BMP8B |
| Hippo signaling pathway | SCRIB,FZD5,BMP7,MPP5,AFP,FZD8,LLGL1,SMAD4,YWHAZ,TEAD2 |
| cAMP signaling pathway | MAPK3,VIPR2,HCN4,HTR1B,MAP2K1,VAV2,PDE3A,GRIN1,FSHR,ATP1A2 |
Protein Function
AMH has several biochemical functions, for example, growth factor activity,hormone activity,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AMH itself. We selected most functions AMH had, and list some proteins which have the same functions with AMH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone activity | SST3,INHBA,Gh,GCGB,PTH1B,UTS2D,PTH1A,INS2,EPO,UTS1 |
| growth factor activity | GMFG,GDNFA,FGF13A,MSTNA,FGF6A,NRTN,MDK,HBEGFB,GSDF,CDNF |
| transforming growth factor beta receptor binding | SMURF2,BMP10,LRG1,NDR2,FKBP1A,MSTNB,BMP7B,BMP8A,TGFB1A,SMAD3 |
| receptor binding | LRRC4B,TAC1,ACOT8,PLA2G1B,SLC39A1,NTF7,DVL3,ZAP70,PVRL4,NPFFL |
Interacting Protein
AMH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMH here. Most of them are supplied by our site. Hope this information will be useful for your research of AMH.
ETV5;ZMAT2;ARL8B
Resources
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References
- Signorile, PG; Baldi, A; et al. A Tissue Specific Magnetic Resonance Contrast Agent, Gd-AMH, for Diagnosis of Stromal Endometriosis Lesions: A Phase I Study. JOURNAL OF CELLULAR PHYSIOLOGY 230:1270-1275(2015).
- Saglam, F; Onal, ED; et al. Anti-Mullerian hormone as a marker of premature ovarian aging in autoimmune thyroid disease. GYNECOLOGICAL ENDOCRINOLOGY 31:165-168(2015).
