AKAP7
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Official Full Name
A kinase (PRKA) anchor protein 7 -
Overview
This gene encodes a member of the A-kinase anchoring protein (AKAP) family, a group of functionally related proteins that bind to a regulatory subunit (RII) of cAMP-dependent protein kinase A (PKA) and target the enzyme to specific subcellular compartments. AKAPs have a common RII-binding domain, but contain different targeting motifs responsible for directing PKA to distinct intracellular locations. Three alternatively spliced transcript variants encoding different isoforms have been described. -
Synonyms
AKAP7;A kinase (PRKA) anchor protein 7;A-kinase anchor protein 7 isoform gamma;AKAP15;AKAP18;A kinase anchor protein 18 kD;A kinase anchor protein 7;A kinase anchor protein 7 isoform alpha;A kinase anchor protein 7 isoform beta;A kinase anchor protein 7 isoform gamma;A kinase anchor protein 7 isoforms alpha and beta;A kinase anchor protein 9 kDa;A kinase anchoring protein 18;AKAP 7;HGNC377;OTTHUMP00000040266;Protein kinase A anchoring protein 7;Protein kinase A anchoring protein 7 isoform alpha;Protein kinase A anchoring protein 7 isoform beta;Protein kinase A anchoring protein 7 isoform gamma;Protein kinase A anchoring protein 7 isoforms alpha/beta;AKAP 18;OTTHUMP00000017200;OTTHUMP00000017201;OTTHUMP00000017202;OTTHUMP00000239966;AKAP-7 isoform gamma;A-kinase anchor protein 9 kDa;A-kinase anchor protein 18 kDa;AKAP-7 isoforms alpha and beta;A-kinase anchor pr
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- E.Coli or Yeast
- Wheat Germ
- Mammalian Cell
- HEK293
- E. coli
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- N-His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
AKAP7 involved in several pathways and played different roles in them. We selected most pathways AKAP7 participated on our site, such as G Protein Signaling Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKAP7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G Protein Signaling Pathways | AKAP6,AKAP13,GNB3B,AKAP1B,AKAP1,GNG13B,Akap3,AKAP10,AKAP5,Akap2 |
Protein Function
AKAP7 has several biochemical functions, for example, nucleotide binding,protein binding,protein kinase A binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AKAP7 itself. We selected most functions AKAP7 had, and list some proteins which have the same functions with AKAP7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase binding | HIF1A,CD226,KCNA5,FOXO3,TSKS,RPS6KA3,SLC12A7,GATA4,NEK6,GCSAM |
| protein kinase A regulatory subunit binding | AKAP9,ACBD3,AKAP1,AKAP5,PRKACA,AKAP8,ARFGEF2,RYR2,EZR,ARFGEF1 |
| nucleotide binding | CHD9,CAMK1DB,MRPL39,RHOAA,Aatk,ATP1A1A.1,STK25A,ARL4CA,TTLL5,DHX57 |
| protein kinase A binding | DACT2,Akap3,AKAP14,AKAP4,NBEA,AKAP17A,AKAP5,AKAP6,DACT3,AKAP12B |
| protein binding | CNOT7,OAS1A,RERG,LYL1,PTMA,PMM2,NLGN4X,HILPDA,PPP2R5D,ODF1 |
Interacting Protein
AKAP7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKAP7 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKAP7.
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