YWHAQ
-
Official Full Name
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide -
Overview
The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, -
Synonyms
YWHAQ;tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide;14-3-3 protein theta;14 3 3;HS1;protein tau;14-3-3 protein tau;14-3-3 protein T-cell;1C5;14-3-3
Recombinant Proteins
- Human
- Chicken
- Rat
- Mouse
- HEK293
- E.coli
- Mammalian Cells
- DDK&Myc
- Non
- His
- GST
- Flag
- Avi&Fc&His
Involved Pathway
YWHAQ involved in several pathways and played different roles in them. We selected most pathways YWHAQ participated on our site, such as Activation of BAD and translocation to mitochondria,Activation of BH3-only proteins,Alpha6-Beta4 Integrin Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with YWHAQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell Cycle Checkpoints | BRCC3,CDK2,RAD9B,MCM10,CDK5RAP2,UIMC1,HUS1,BARD1,UBE2V2,THRSP |
| Alpha6-Beta4 Integrin Signaling Pathway | DST,EIF4E,NTN1A,EGFR,COL17A1,EIF4EB,PLEC,SMAD3B,CD151L,CD151 |
| Apoptosis | BNIP3LB,JUN,TNFRSF10B,AIFM1,PPP3CCA,CASP8,TP53,HIST1H1A,CASP3A,PRKAR2A |
| Activation of BH3-only proteins | BCL2L11,CDK5RAP2,DYNLL2,E2F1,AKT3 |
| Cell cycle | SGOL1,CDC7,CEP72,DHFR,H3F3B.1,SMAD3,CCNB3,CCNE1,PMF1,GSK3AA |
| Activation of BAD and translocation to mitochondria | CDK5RAP2,AKT3 |
| Calcium Regulation in the Cardiac Cell | GJB4,GJB1,GJA3,KCNJ3,ANXA6,GJA10,CCDC102A,CX44.1,CHRM5,KCNJ5 |
Protein Function
YWHAQ has several biochemical functions, for example, 14-3-3 protein binding,ion channel binding,protein C-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by YWHAQ itself. We selected most functions YWHAQ had, and list some proteins which have the same functions with YWHAQ. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 14-3-3 protein binding | HDAC7,IRS2,TSC2,KIF13B,PRKCE,AANAT,RPTOR,KCNH1,DDIT4,SRPK2 |
| protein N-terminus binding | TRAF6,TBL1XR1,EXOC5,SLA2,MAU2,HDAC1,MEN1,SNF8,STXBP1,RPS21 |
| protein C-terminus binding | SDC1,TAF13,C11orf60,SDCBP,NIPBL,CITED1,PEX5,FOXN3,HPCAL4,TCF4 |
| protein binding | UNC45B,PBXIP1,FAM82A2,LMX1A,RPA2,CUEDC2,MC5R,Cd24a,C10orf81,CYHR1 |
| protein domain specific binding | HIST1H4L,RAPGEF3,ARFIP2A,CAPG,ERCC1,NLRP1,NEFL,TACC3,CRB3,CASKIN1 |
| ion channel binding | FGF13,RANGRF,PACS2,DLG1,FAM115A,FXYD1,HSP90AB1,CDH5,SRI,KCNAB1 |
Interacting Protein
YWHAQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with YWHAQ here. Most of them are supplied by our site. Hope this information will be useful for your research of YWHAQ.
LRRK2;EGFR;YAP1;CBL
Resources
Research Area
Apoptosis Adaptor ProteinsAdaptor Proteins
phospho-Serine/phospho-Threonine Binding Proteins
Adaptor Proteins in the Akt Pathway
Apical-basal Polarity Effectors
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References
