XAF1
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Official Full Name
XIAP associated factor 1 -
Overview
This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of;apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The;proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress;of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this;gene. -
Synonyms
XAF1;XIAP associated factor 1;XIAP-associated factor 1;BIRC4BP;HSXIAPAF1;XIAPAF1;BIRC4 binding protein;BIRC4-binding protein
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- His
- GST
- Non
- His&Fc&Avi
- His&GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| XAF1-185H | Recombinant Human XAF1, His-tagged | E.coli | Human | His | 1- 125aa |
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| XAF1-18600M | Recombinant Mouse XAF1 Protein | Mammalian Cells | Mouse | His |
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| XAF1-227H | Recombinant Human XAF1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| XAF1-5226R | Recombinant Rhesus monkey XAF1 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| XAF1-271HCL | Recombinant Human XAF1 293 Cell Lysate | HEK293 | Human | Non |
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| XAF1-10219M | Recombinant Mouse XAF1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| XAF1-10219M-B | Recombinant Mouse XAF1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| XAF1-225H | Recombinant Human XAF1 Protein, GST/His-tagged | E.coli | Human | His&GST |
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| XAF1-5039R | Recombinant Rhesus Macaque XAF1 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| XAF1-5039R-B | Recombinant Rhesus Macaque XAF1 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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Involved Pathway
XAF1 involved in several pathways and played different roles in them. We selected most pathways XAF1 participated on our site, such as Cytokine Signaling in Immune system,Immune System,Interferon Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with XAF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | LILRA3,DDX41,DEFB125,HAVCR2,POLR3F,DZIP3,S100A12,RAET1E,TXNIPA,HUWE1 |
| Cytokine Signaling in Immune system | SOCS3A,IFIT3,SPRED3,CASPB,IRF9,GBP5,PRLRB,DUSP5,EIF4E3,IFITM2 |
| Interferon Signaling | IFI27,IFIT12,IFIT8,GBP4,IFITM2,IFIT3,TRIM62,FCGR1B,ISG20,IFIT11 |
| Interferon alpha/beta signaling | IFI6,IRF4,IRF9,MX2,ISG20,IFIT2,OASL,IFIT3,GBP2,USP18 |
Protein Function
XAF1 has several biochemical functions, for example, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by XAF1 itself. We selected most functions XAF1 had, and list some proteins which have the same functions with XAF1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | SOLH,PDZRN4,ZFP276,GDA,PPARDB,PTPN1,NR1D2A,GRIN2B,PCGF6,ADAM15 |
Interacting Protein
XAF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with XAF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of XAF1.
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References
- Long, XG; Li, Y; et al. XAF1 contributes to dengue virus-induced apoptosis in vascular endothelial cells. FASEB JOURNAL 27:1062-1073(2013).
- Serrano-Fernandez, P; Moller, S; et al. Time course transcriptomics of IFNB1b drug therapy in multiple sclerosis. AUTOIMMUNITY 43:172-178(2010).
