WNT5B

  • Official Full Name

    wingless-type MMTV integration site family, member 5B

  • Overview

    The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants.

  • Synonyms

    WNT5B;wingless-type MMTV integration site family, member 5B;protein Wnt-5b;WNT-5B protein;MGC2648

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • Zebrafish
  • Cattle
  • E.coli
  • CHO
  • Mammalian Cell
  • Human Cell
  • HEK293
  • His
  • Non
  • StrepII
  • His&Fc&Avi
  • His&T7
  • His&GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
WNT5B-3053H Recombinant Human WNT5B protein, His-tagged E.coli Human His 128-267 aa
Wnt5b-303M Active Recombinant Mouse Wnt5b CHO Mouse Non 31-372 a.a.
WNT5B-773H Active Recombinant Human WNT5B CHO Human Non Gln18-Lys359
WNT5B-18574M Recombinant Mouse WNT5B Protein Mammalian Cell Mouse His
WNT5B-207H Recombinant Human WNT5B, StrepII-tagged Human Cell Human StrepII 18-359, 342 a.a.
WNT5B-3289C Recombinant Chicken WNT5B Mammalian Cell Chicken His
WNT5B-8578Z Recombinant Zebrafish WNT5B Mammalian Cell Zebrafish His
WNT5B-291HCL Recombinant Human WNT5B 293 Cell Lysate HEK293 Human Non
WNT5B-292HCL Recombinant Human WNT5B 293 Cell Lysate HEK293 Human Non
WNT5B-10199M Recombinant Mouse WNT5B Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
WNT5B-10199M-B Recombinant Mouse WNT5B Protein Pre-coupled Magnetic Beads HEK293 Mouse
WNT5B-119H Active Recombinant Human WNT5B Protein E.coli Human
WNT5B-1478C Recombinant Cattle WNT5B protein, His & T7-tagged E.coli Cattle His&T7 Met30~Lys358
WNT5B-587H Recombinant Human WNT5B Protein, His&GST-tagged E.coli Human His&GST Gln18-Lys359

    Involved Pathway

    WNT5B involved in several pathways and played different roles in them. We selected most pathways WNT5B participated on our site, such as Wnt signaling pathway,Hedgehog signaling pathway,Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hedgehog signaling pathway GAS1,WNT11R,CSNK1G2A,ZIC2,SKIA,GLI1,FBXW11A,BMP4,PRKACB,CSNK1G2
    Proteoglycans in cancer WNT10B,Casp3,PAK1,HOXD10,PLCG1,SDC2,TWIST1,PRKCA,HPSE2,PRKACG
    Wnt signaling pathway LRP5,BAMBIA,WNT10B,SIAH2L,CSNK2A2A,ROCK2A,FZD3B,DKK2,CER1,FOSL1A
    Pathways in cancer PLCG1,PRKACB,PDGFA,KITLG,CKS2,FGF1,NKX3-1,TRP53,WNT8A,GNG11
    Signaling pathways regulating pluripotency of stem cells KLF4,REST,BMI1,SMAD9,OTX1,PIK3CD,WNT2,MAPK13,FGF2,WNT7A
    Basal cell carcinoma BMP2,WNT8A,WNT2B,APC2,FZD10,SMO,SETD6,WNT11,WNT7B,TRP53
    HTLV-I infection CDC20,PRKACB,AKT2,GM-CSF,TRP53INP1,POLE2,APC,CRTC2,MAP3K14,POLE3
    Hippo signaling pathway FZD3,TEAD1,BTRC,WNT3A,LEF1,BMP4,TGFB3,ACTB,PARD6A,SMAD4
    Melanogenesis CALM1B,WNT9A,FZD9B,CREB3L3,TCF7L1A,DVL3A,CREB3L2,MAP2K2,CALM3,FZD8A

    Protein Function

    WNT5B has several biochemical functions, for example, frizzled binding,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT5B itself. We selected most functions WNT5B had, and list some proteins which have the same functions with WNT5B. You can find most of the proteins on our site.

    Function Related Protein
    receptor binding GUSB,P2RX7,FGF10A,DDX54,BMP3,FGF11,CD2,MSN,ADIPOQ,KCNA5
    frizzled binding WNT3A,WNT2BB,WNT4,WNT2B,WNT4A,WNT10B,ZNRF3,ROR2,SDCBP,WNT9A

    Interacting Protein

    WNT5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT5B here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT5B.

    APPBP2

    WNT5B Related Signal Pathway

    Resources

    Gene Families

    What Is Wingless-INT (WNT)

    Research Area

    Wnt Ligands (Wnts)

    References

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