UNC5C
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Official Full Name
unc-5 homolog C (C. elegans) -
Overview
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. -
Synonyms
UNC5C;unc-5 homolog C (C. elegans);unc5 (C.elegans homolog) c;netrin receptor UNC5C;UNC5H3;homolog of C. elegans transmembrane receptor Unc5;Protein unc 5 homolog C;Unc 5 homolog 3;Unc 5 homolog C;unc-5 homolog 3;OTTHUMP00000161619;OTTHUMP00000219358;protein unc-5 homolog 3;protein unc-5 homolog C
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Rat
- E.coli
- Mammalian Cells
- HEK293
- GST
- Fc
- His
- Avi&Fc&His
- DDK&Myc
Involved Pathway
UNC5C involved in several pathways and played different roles in them. We selected most pathways UNC5C participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with UNC5C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Axon guidance | EPHA8,CSNK2A2,HBEGF,PPP3CC,EFNB2,EPHB4B,FGFR1B,TRPC7,RAC3,MYL12B |
Protein Function
UNC5C has several biochemical functions, for example, netrin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UNC5C itself. We selected most functions UNC5C had, and list some proteins which have the same functions with UNC5C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| netrin receptor activity | Unc5b |
Interacting Protein
UNC5C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UNC5C here. Most of them are supplied by our site. Hope this information will be useful for your research of UNC5C.
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