TSPAN7
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Official Full Name
tetraspanin 7 -
Overview
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntingtons chorea, fragile X syndrome and myotonic dystrophy. -
Synonyms
TSPAN7;tetraspanin 7;mental retardation, X linked 58 , MRX58, MXS1, TM4SF2, transmembrane 4 superfamily member 2;tetraspanin-7;A15;CD231;DXS1692E;TALLA 1;CD231 antigen;Cell surface glycoprotein A15;Membrane component X chromosome surface marker 1;T cell acute lymphoblastic leukemia associated antigen 1;Transmembrane 4 superfamily member 2;Tspan 7;tspan-7;tetraspanin protein;transmembrane protein A15;transmembrane 4 superfamily 2b;membrane component chromosome X surface marker 1;membrane component, X chromosome, surface marker 1;T-cell acute lymphoblastic leukemia associated antigen 1;T-cell acute lymphoblastic leukemia-associated antigen 1;MXS1;MRX58;CCG-B7;TM4SF2;TALLA-1;TM4SF2b
Recombinant Proteins
- Human
- Cynomolgus
- Zebrafish
- Rat
- Rhesus macaque
- Mouse
- Mus musculus
- Pongo Pygmaeus
- Pan troglodytes
- Insect Cells
- Human Cells
- Mammalian Cells
- HEK293
- Wheat Germ
- E.coli
- Yeast
- In Vitro Cell Free System
- His
- Non
- Flag
- mFc
- His&Fc&Avi
Involved Pathway
TSPAN7 involved in several pathways and played different roles in them. We selected most pathways TSPAN7 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with TSPAN7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Transcriptional misregulation in cancer | MEN1,HIST2H3C1,PML,HOXA11,RUNX2,MLL1,NFKBIZ,ASPSCR1,TGFBR2,MPO |
Protein Function
TSPAN7 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by TSPAN7 itself. We selected most functions TSPAN7 had, and list some proteins which have the same functions with TSPAN7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
TSPAN7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSPAN7 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSPAN7.
RBL1;CACNA1A;CREB3
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