TSPAN4
-
Official Full Name
tetraspanin 4 -
Overview
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
TSPAN4;tetraspanin 4;TM4SF7, transmembrane 4 superfamily member 7;tetraspanin-4;NAG 2;TETRASPAN;TSPAN 4;novel antigen 2;tetraspan TM4SF;transmembrane 4 superfamily member 7;NAG2;NAG-2;TM4SF7;TSPAN-4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TSPAN4-3856H | Recombinant Human TSPAN4 protein, His-tagged | E.coli | Human | His | 96-212 aa | |
| TSPAN4-707HCL | Recombinant Human TSPAN4 293 Cell Lysate | HEK293 | Human | Non |
|
|
| TSPAN4-708HCL | Recombinant Human TSPAN4 293 Cell Lysate | HEK293 | Human | Non |
|
|
| RFL23946HF | Recombinant Full Length Human Tetraspanin-4(Tspan4) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-238) |
|
| RFL24471PF | Recombinant Full Length Pongo Abelii Tetraspanin-4(Tspan4) Protein, His-Tagged | E.coli | Pongo Abelii | His | Full L. Full Length (1-238) |
|
| RFL9349MF | Recombinant Full Length Mouse Tetraspanin-4(Tspan4) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-238) |
|
Involved Pathway
TSPAN4 involved in several pathways and played different roles in them. We selected most pathways TSPAN4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TSPAN4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TSPAN4 has several biochemical functions, for example, antigen binding,integrin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TSPAN4 itself. We selected most functions TSPAN4 had, and list some proteins which have the same functions with TSPAN4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RPL10,SYT11,WDTC1,HBB,ARSA,FKBPL,INHA,MRC1,HM13,BLCAP |
| integrin binding | TNN,ITGB1BP2,COL3A1,CTGFB,ITGB1,CTGF,LYN,COL5A1,FN1,CIB2 |
| antigen binding | LILRA2,IGKV1-5,IGLL1,FCN2,MHC1UKA,PPP2R1A,IL7R,IGKC,IGHM,HNRNPM |
Interacting Protein
TSPAN4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSPAN4 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSPAN4.
NOTCH2NL;CREB3
Resources
Related Services
Related Products
References
- Tang, QH; Liu, ZY; et al. Involvement of activation of C-met signaling pathway in CD151-induced HUVECs angiogenesis. JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES 35:35-41(2015).
- Pagel, JM; Spurgeon, SE; et al. Otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR (TM) therapeutic protein, for relapsed or refractory NHL patients. BRITISH JOURNAL OF HAEMATOLOGY 168:38-45(2015).
