TSPAN12
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Official Full Name
tetraspanin 12 -
Overview
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. -
Synonyms
TSPAN12;tetraspanin 12;TM4SF12, transmembrane 4 superfamily member 12;tetraspanin-12;NET 2;AI663988;TSPAN 12;9030619E17;AI426782;AW111457;MGC109305;NET2;OTTHUMP00000211224;Tetraspan NET 2;Tetraspanin12;TM4SF12;Transmembrane 4 superfamily member 12;tspan-12;tetraspan NET-2;EVR5;NET-2
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Rat
- Bovine
- Mus musculus
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
TSPAN12 involved in several pathways and played different roles in them. We selected most pathways TSPAN12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TSPAN12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TSPAN12 has several biochemical functions, for example, NOT Wnt-activated receptor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TSPAN12 itself. We selected most functions TSPAN12 had, and list some proteins which have the same functions with TSPAN12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | VPS29,GCNT1,NLRP1,LOXL2,KIF1C,PFKFB1,NQO2,PPARGC1A,UBE2V2,HSPA1L |
| NOT Wnt-activated receptor activity | SFRP2,FRZB,SFRP1A,SFRP1,SZL,SMO,SETD6,SFRP4,SFRP1B |
Interacting Protein
TSPAN12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TSPAN12 here. Most of them are supplied by our site. Hope this information will be useful for your research of TSPAN12.
TFCP2;q5ngw2_fratt;NDP;FZD4
Resources
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References
- Pagel, JM; Spurgeon, SE; et al. Otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR (TM) therapeutic protein, for relapsed or refractory NHL patients. BRITISH JOURNAL OF HAEMATOLOGY 168:38-45(2015).
- Gopal, AK; Tarantolo, SR; et al. Phase 1b study of otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR (TM) therapeutic protein, in combination with rituximab and bendamustine in relapsed indolent lymphoma patients. INVESTIGATIONAL NEW DRUGS 32:1213-1225(2014).
