TRIM24
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Official Full Name
tripartite motif containing 24 -
Overview
TIF1beta is a member of the TIF1 (transcriptional intermediary factor 1) family, a group of transcriptional regulators that play key roles in development and differentiation. Members of this family are characterized by the presence of two conserved motifs -
Synonyms
TRIM24;tripartite motif containing 24;TIF1, transcriptional intermediary factor 1 , tripartite motif containing 24;transcription intermediary factor 1-alpha;hTIF1;RNF82;TIF1A;TIF1-alpha;RING finger protein 82;tripartite motif-containing
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Zebrafish
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- Yeast
- Insect Cells
- In Vitro Cell Free System
- His
- GST
- Flag
- Non
- SUMO
- Avi
- Fc
Involved Pathway
TRIM24 involved in several pathways and played different roles in them. We selected most pathways TRIM24 participated on our site, such as Disease,Diseases of signal transduction,FGFR1 mutant receptor activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM24 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Regulation of Androgen receptor activity | KAT7,NR2C2,GATA2,SMARCA2,SMARCE1,APPBP2,NR0B1,SENP1,HOXB13,SRY |
| Signaling by FGFR1 in disease | MYO18A,FGFR1OP2,CUX1,CPSF6 |
| Signaling by FGFR in disease | CUX1,LRRFIP1,CPSF6,MYO18A,FGFR1OP2 |
| Signaling by FGFR1 fusion mutants | CPSF6,CUX1,MYO18A,FGFR1OP2 |
| Diseases of signal transduction | OPN1MW2,RLBP1,MIB1,CCNC,LRRFIP1,CDK8,CUX1,CPSF6,KREMEN2,KREMEN1 |
| Disease | OPN1MW,RLBP1,PRELP,ACAN,RPL35,AP2B1,OPN1LW,FDX1L,PPIA,RDBP |
| FGFR1 mutant receptor activation | FGFR1OP,FGFR1OP2,CPSF6,MYO18A,CUX1,LRRFIP1 |
Protein Function
TRIM24 has several biochemical functions, for example, chromatin binding,estrogen response element binding,ligand-dependent nuclear receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM24 itself. We selected most functions TRIM24 had, and list some proteins which have the same functions with TRIM24. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ubiquitin protein ligase activity | HERC5,TOPORS,UBR2,PJA2,RAG1,CDC34,UBE2J2,UBE2G1,UBR3,HERC3 |
| p53 binding | BRD4,USP10,SIRT1,BRD7,DUSP26,PTTG1IP,TRP53,EHMT2,MAPKAPK5,NUAK1 |
| NOT methylated histone binding | CDYL |
| protein binding | ERCC6L,CCNK,OLIG3,ARL13B,BCL7B,JRK,REST,CAV3,RNF32,C10orf46 |
| estrogen response element binding | TOX3,ESR1,ESR2 |
| lysine-acetylated histone binding | TAF1L,TAF1,BAZ2A,PHIP,SMARCA4,BRD7,BRDT,BAZ1B,PSME4,PSME4B |
| receptor binding | FGF1A,PTK2BB,TESPA1,NXPH1,TNFSF10,NUDT19,ARRB2,HSD17B4,MSN,F2R |
| sequence-specific DNA binding | E2F1,BATF,ARXA,CAMTA2,ZFP42,HOXB5A,MEOX2B,HOXC6A,ZFP423,MAFF |
| ligase activity | PJA2,RAG1,HACE1,UBE2D1A,CDC34B,RC3H2,XIAP,TRIM68,UBR3,MKRN2 |
Interacting Protein
TRIM24 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM24 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM24.
HSPB1;BRCA1;UBE2U;RNF141;TRIM8;RNF181;pi3p;ESR1;ESR2;TRIM33
TRIM24 Related Signal Pathway
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