Tox

  • Official Full Name

    thymocyte selection-associated high mobility group box

  • Overview

    The protein encoded by this gene contains a HMG box DNA binding domain. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. This protein may function to regulate T-cell development.

  • Synonyms

    TOX;thymocyte selection-associated high mobility group box;thymocyte selection-associated high mobility group box protein TOX;KIAA0808;TOX1;Thymus high mobility group box protein TOX;TOX 1

Recombinant Proteins

  • Human
  • Chicken
  • Rhesus macaque
  • Zebrafish
  • Mouse
  • E.coli
  • Pseudomonas Fluorescens
  • Mammalian Cells
  • HEK293
  • GST
  • Non
  • His
  • Flag
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
TOX-3358H Recombinant Human TOX, GST-tagged E.coli Human GST N-term-331aa
CRM197-2780C Recombinant CRM197 Pseudomonas Fluorescens Non
TOX-2705C Recombinant Chicken TOX Mammalian Cells Chicken His
TOX-4908R Recombinant Rhesus monkey TOX Protein, His-tagged Mammalian Cells Rhesus macaque His
TOX-8190Z Recombinant Zebrafish TOX Mammalian Cells Zebrafish His
TOX-863HCL Recombinant Human TOX 293 Cell Lysate HEK293 Human Non
TOX-1411HFL Recombinant Full Length Human TOX Protein, C-Flag-tagged Mammalian Cells Human Flag Full L.
TOX-2234H Recombinant Human TOX Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
TOX-2234H-B Recombinant Human TOX Protein Pre-coupled Magnetic Beads HEK293 Human
TOX-4722R Recombinant Rhesus Macaque TOX Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
TOX-4722R-B Recombinant Rhesus Macaque TOX Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
Tox-6588M Recombinant Mouse Tox Protein, Myc/DDK-tagged HEK293 Mouse Myc&DDK

    Involved Pathway

    Tox involved in several pathways and played different roles in them. We selected most pathways Tox participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Tox were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    Tox has several biochemical functions, for example, DNA binding,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Tox itself. We selected most functions Tox had, and list some proteins which have the same functions with Tox. You can find most of the proteins on our site.

    Function Related Protein
    chromatin binding SMAD2,IFT74,NKX2-5,DNMT1,TADA2A,NEUROD1,FOXO1,HHEX,CCDC111,PRKCB
    DNA binding ARID5A,IRX1B,ZNF571,LBX1,ZFP35,TAL2,HIST1H4B,TOPORS,RNF6,POLR3A

    Interacting Protein

    Tox has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Tox here. Most of them are supplied by our site. Hope this information will be useful for your research of Tox.

    ZDHHC17

    Resources

    References

    • Lehmann, D; Spanholtz, J; et al. IL-12 Directs Further Maturation of Ex Vivo Differentiated NK Cells with Improved Therapeutic Potential. PLOS ONE 9:-(2014).
    • Meschenmoser, K; Kim, Y; et al. Targeting Cancer with a Bi-functional Peptide: In Vitro and In Vivo Results. IN VIVO 27:431-442(2013).

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