TNK1
-
Official Full Name
tyrosine kinase, non-receptor, 1 -
Overview
Tyrosine kinase non-receptor 1 (TNK1) is related to the Ack1 (TNK2) non-receptor kinase that binds cdc42 and inhibits GTPase activity of this cell cycle regulator. TNK1 is broadly expressed in embryogenic tissues and leukemia cell lines, but is restricted -
Synonyms
TNK1;tyrosine kinase, non-receptor, 1;non-receptor tyrosine-protein kinase TNK1;CD38 negative kinase 1;MGC46193
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TNK1-3326H | Recombinant Human TNK1, His-tagged | E.coli | Human | His | 1-377aa | |
| TNK1-701H | Recombinant Human Tyrosine Kinase, Non-receptor, 1, GST-tagged | Insect Cells | Human | GST | 106-390 a.a. |
|
| TNK1-886HCL | Recombinant Human TNK1 293 Cell Lysate | HEK293 | Human | Non |
|
|
| TNK1-11H | Recombinant Human TNK1 Protein (Full Length), N-His tagged | E.coli | Human | His | Full L. Full Length |
|
| TNK1-702H | Active Recombinant Human TNK1 Protein (1-510aa), N-GST tagged | Sf9 Cells | Human | GST | 1-510 a.a. |
|
Involved Pathway
TNK1 involved in several pathways and played different roles in them. We selected most pathways TNK1 participated on our site, such as Focal Adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with TNK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Focal adhesion | AKT2L,TNK2,MAP2K1,ITGB3B,PPP1CB,RAF1A,SHC3,BAD,CDC42L2,COL24A1 |
Protein Function
TNK1 has several biochemical functions, for example, ATP binding,hormone receptor binding,non-membrane spanning protein tyrosine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TNK1 itself. We selected most functions TNK1 had, and list some proteins which have the same functions with TNK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| signal transducer activity | JUP,GAB1,FPR-RS3,PLCB2,COPS2,OLFR13,ECM1,LSP1,STAT2,ADRA1BB |
| protein tyrosine kinase activity | TTK,FGR,MET,TESK2,LTK,MAP3K11,CSF1RA,JAK2A,ERBB4A,KIAA1804 |
| hormone receptor binding | TNK2,SRC,JAK2A,JAK2B,TNK2B,JAK3 |
| non-membrane spanning protein tyrosine kinase activity | ABL1,PTK2,MATK,STK16,CLK1,DYRK1A,FES,JAK2,PTK2B,JAK1 |
| ATP binding | ENTPD8,PRPS1,HSP90AA1,CLPX,STK25A,MYO7B,EIF2AK2,TSSK4,MARK2,PRKCH |
| protein binding | CEP350,MSH2,JUND,FSTL1,KRTAP3-2,FRAS1,KLRC2,LINC01588,FAAH,NDRG1 |
Interacting Protein
TNK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TNK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TNK1.
SFN;b4dyc6_human;xmd8-92;biotin_acyl-p_probe;HSP90AB1;CDC37;pi3p;czc8004;linkable pd173955 analogue;linkable vandetanib analogue;linkable sunitinib analogue;linkable staurosporine analogue;linkable imatinib analogue;bosutinib;bisindolylmaleimide iii;imatinib
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