TMPRSS15
-
Official Full Name
transmembrane protease, serine 15 -
Overview
This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive. -
Synonyms
TMPRSS15;transmembrane protease, serine 15;protease, serine, 7 (enterokinase) , PRSS7;enteropeptidase;ENTK;MGC133046;proenterokinase;PRSS 7;PRSS7;Serine protease 7;Enterokinase;Enteropeptidase catalytic light chain;Enteropeptidase non catalytic heavy chain;ENTK_HUMAN;protease, serine, 7 (enterokinase);Transmembrane protease serine 15;OTTHUMP00000083248
Recombinant Proteins
- Mouse
- Human
- Pig
- Bovine
- Sus scrofa (Pig)
- Cattle
- Rat
- HEK293
- E.coli
- Human
- CHO
- Yeast
- Porcine
- P.pastoris
- His
- Non
- GST
- His&SUMO
- His&Myc
- Avi&Fc&His
Involved Pathway
TMPRSS15 involved in several pathways and played different roles in them. We selected most pathways TMPRSS15 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TMPRSS15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TMPRSS15 has several biochemical functions, for example, protein binding,scavenger receptor activity,serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TMPRSS15 itself. We selected most functions TMPRSS15 had, and list some proteins which have the same functions with TMPRSS15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| scavenger receptor activity | TMPRSS5,ABHD1,TMPRSS4A,LOXL3,ENPP1,TMPRSS4,LOXL3A,SCART1,MARCO,ENPP2 |
| serine-type endopeptidase activity | HTRA1B,HTRA2,MMP8,F11,CELA2A,TMPRSS2,OVCH2,PRTN3,TYSND1,AZU1 |
| protein binding | SPRED1,RXFP1,BNIPL,LNX2,RNF126,KIF1C,OLIG3,F11R,MTUS2,UHMK1 |
Interacting Protein
TMPRSS15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TMPRSS15 here. Most of them are supplied by our site. Hope this information will be useful for your research of TMPRSS15.
Tnfrsf11a;TNFRSF11A;PYCARD
Resources
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References
