TIMELESS
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Official Full Name
timeless homolog (Drosophila) -
Synonyms
TIMELESS;timeless homolog (Drosophila);timeless (Drosophila) homolog;protein timeless homolog;hTIM;TIM;TIM1;TIM_HUMAN;TIMELESS1;OTTHUMP00000244115;OTTHUMP00000244116
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Flag
- Avi
- Fc
- DDK
- Myc
Involved Pathway
TIMELESS involved in several pathways and played different roles in them. We selected most pathways TIMELESS participated on our site, such as Circadian rhythm pathway,DNA Double-Strand Break Repair,DNA Repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with TIMELESS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| DNA Double-Strand Break Repair | THRSP,EYA3,PARP2,UBE2V2,BRE,KDM4A,FAM175A,FUZ,DNA2,PPP4CB |
| Circadian rhythm pathway | DEC1,CHEK1,NONO |
| Homology Directed Repair | RHNO1,EME2,FUZ,EME1,PPP4R2A,RTEL1,KIAA0146,PPP4CB,WRN,GEN1 |
| HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) | UIMC1,RHNO1,RTEL1,THRSP,RAD1,RAD9,RAD51AP1,BRE,BABAM1,RNF168 |
| DNA Repair | ACTL6A,FAM175A,MGMT,TOPBP1,KIAA0101,ZBTB32,TP53BP1,PPP4CB,ASCC1,USP43A |
| Processing of DNA double-strand break ends | PPP4CA,PPP4R2B,PPP4R2A,TIPIN,PPP4CB,PPP4R2 |
Protein Function
TIMELESS has several biochemical functions, for example, protein binding,protein heterodimerization activity,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TIMELESS itself. We selected most functions TIMELESS had, and list some proteins which have the same functions with TIMELESS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | JAM3,UNC45A,TBC1D5,GABARAPL2,MAGEE1,NHP2L1,KCNA1,CDKN2B,ARHGAP4,TNFRSF6B |
| protein heterodimerization activity | GABRR1,HIST1H2B7,NR2C2,TOP2B,HIST4H4,NFYBA,SMC4,RALGAPA2,MID1,PPP3CA |
| protein homodimerization activity | SLC51A,HELT,IL12B,RAB11FIP3,DNM1L,SERPINF2,PTPRE,TYRP1,UGT1A6B,HSP90AA1 |
Interacting Protein
TIMELESS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TIMELESS here. Most of them are supplied by our site. Hope this information will be useful for your research of TIMELESS.
Tipin;CHEK1;CRY2;Timeless;TF;RPA2;RPA1;RPA3;ATR;ATRIP;PRIMPOL
Resources
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References
- Schepeler, T; Lamy, P; et al. A high resolution genomic portrait of bladder cancer: correlation between genomic aberrations and the DNA damage response. ONCOGENE 32:3577-3586(2013).
- Martins, AR; Zanella, CAB; et al. Immunolocalization of nitric oxide synthase isoforms in human archival and rat tissues, and cultured cells. JOURNAL OF NEUROSCIENCE METHODS 198:16-22(2011).
