TFEB

  • Official Full Name

    transcription factor EB

  • Overview

    Transcription factor EB (TFEB) specifically recognizes and binds E-box sequences (3-CANNTG-5). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, TFEB activates the

  • Synonyms

    TFEB;transcription factor EB;bHLHe35;TCFEB;T-cell transcription factor EB;class E basic helix-loop-helix protein 35;ALPHATFEB

Recombinant Proteins

  • Human
  • Chicken
  • Rhesus macaque
  • Zebrafish
  • E.coli
  • Wheat Germ
  • Mammalian Cells
  • HEK293
  • GST
  • His
  • T7
  • Flag
  • TEV
  • Avi
  • Fc
Cat.# Product name Source (Host) Species Tag Protein Length Price
TFEB-3202H Recombinant Human TFEB, GST-tagged E.coli Human GST 1-476aa
TFEB-14HFL Recombinant Full Length Human transcription factor EB Protein, N-GST tagged Wheat Germ Human GST Full L. 1-476 aa
TFEB-212H Recombinant Human TFEB protein, T7/His-tagged E.coli Human His&T7 475 a.a.
TFEB-2611C Recombinant Chicken TFEB Mammalian Cells Chicken His
TFEB-4680R Recombinant Rhesus monkey TFEB Protein, His-tagged Mammalian Cells Rhesus macaque His
TFEB-635H Recombinant Human TFEB Protein, His-tagged E.coli Human His 1-476aa
TFEB-8212Z Recombinant Zebrafish TFEB Mammalian Cells Zebrafish His
TFEB-1128HCL Recombinant Human TFEB 293 Cell Lysate HEK293 Human Flag 1-476aa
TFEB-12H Recombinant Full Length Human transcription factor EB Protein, T7&His&TEV tagged E.coli Human His&T7&TEV Full L.
TFEB-4496R Recombinant Rhesus Macaque TFEB Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
TFEB-4496R-B Recombinant Rhesus Macaque TFEB Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
TFEB-6591H Recombinant Full Length Human TFEB Protein (Met1-Leu476), N-His tagged E.coli Human His Full L. 1-476 a.a.
TFEB-6592H Recombinant Human TFEB protein, His-tagged E.coli Human His Glu221-Pro380

    Involved Pathway

    TFEB involved in several pathways and played different roles in them. We selected most pathways TFEB participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TFEB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    TFEB has several biochemical functions, for example, protein dimerization activity,transcription factor activity, sequence-specific DNA binding,transcription regulatory region DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TFEB itself. We selected most functions TFEB had, and list some proteins which have the same functions with TFEB. You can find most of the proteins on our site.

    Function Related Protein
    protein dimerization activity MEF2CB,PIP,SIM1A,SIM1B,ANO4,POLR1D,SRFB,MYO5A,MYCLB,HIF1AL2
    transcription regulatory region DNA binding NFKB1,NKX3,NFE2L2,MEN1,TBL1XR1,TCF7L1B,RFX3,MTERFD3,GRHL2B,MSX2
    transcription factor activity, sequence-specific DNA binding RFX1A,ESR2B,NFKB2,ZNF484,HIVEP2A,IKZF2,ZFP42,TAF13,MEF2C,TFE3

    Interacting Protein

    TFEB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFEB here. Most of them are supplied by our site. Hope this information will be useful for your research of TFEB.

    SRPK1;q81ni5_bacan;PPM1G;MITF;BAG2;MT-CO2;IFIT1;MAPT;ATP5J;TFE3;STT3A;C10orf12;EML4;TBC1D14

    Resources

    Research Area

    Other Autophagy-related Proteins

    References

    • Moch, H; Montironi, R; et al. Oncotargets in Different Renal Cancer Subtypes. CURRENT DRUG TARGETS 16:125-135(2015).
    • Tan, PH; Cheng, L; et al. Renal Tumors Diagnostic and Prognostic Biomarkers. AMERICAN JOURNAL OF SURGICAL PATHOLOGY 37:1518-1531(2013).

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