TFB2M
-
Official Full Name
transcription factor B2, mitochondrial -
Overview
Dimethyladenosine transferase 2, mitochondrial is an enzyme that in humans is encoded by the TFB2M gene. -
Synonyms
TFB2M;transcription factor B2, mitochondrial;dimethyladenosine transferase 2, mitochondrial;FLJ22661;FLJ23182;Hkp1;HCV NS5A transactivated protein 5;Mitochondrial 12S rRNA dimethylase 2;mitochondrial;Mitochondrial transcription factor B2;mtTFB2;N-adenosyl(rRNA) dimethyltransferase 2;S adenosylmethionine 6 N, N adenosyl(rRNA) dimethyltransferase 2;Dimethyladenosine transferase 2;h-mtTFB;h-mtTFB2;HCV NS5A-transactivated protein 5;Hepatitis C virus NS5A-transactivated protein 5;hTFB2M;Mitochondrial dimethyladenosine transferase 2;mtTFB;NS5ATP5;S-adenosylmethionine-6-N;TFB2M_HUMAN;Transcription Factor B2;OTTHUMP00000037974;S-adenos
Recombinant Proteins
- Human
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TFB2M-3195H | Recombinant Human TFB2M, His-tagged | E.coli | Human | His | c-221aa | |
| TFB2M-1580H | Recombinant Human TFB2M protein | E.coli | Human | Non |
|
|
| TFB2M-6026R | Recombinant Rat TFB2M Protein | Mammalian Cell | Rat | His |
|
|
| TFB2M-6345Z | Recombinant Zebrafish TFB2M | Mammalian Cell | Zebrafish | His |
|
|
| TFB2M-7205H | Recombinant Human Transcription Factor B2, Mitochondrial, His-tagged | E.coli | Human | His | 20-396aa |
|
| TFB2M-1135HCL | Recombinant Human TFB2M 293 Cell Lysate | HEK293 | Human | Non |
|
|
| Tfb2m-1131M | Recombinant Mouse Tfb2m Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
|
| TFB2M-5685R | Recombinant Rat TFB2M Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| TFB2M-5685R-B | Recombinant Rat TFB2M Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
||
| TFB2M-696H | Recombinant Human TFB2M Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
|
Involved Pathway
TFB2M involved in several pathways and played different roles in them. We selected most pathways TFB2M participated on our site, such as Energy Metabolism,Gene Expression,Mitochondrial Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFB2M were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Organelle biogenesis and maintenance | CCDC123,BBS10,TUFM,TTBK2,TNPO1,LZTFL1,CCDC41,IFT81,RP2,MRRF |
| Transcription from mitochondrial promoters | MTERF,POLRMT |
| RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription | SNAPC5,POU2F1,SNAPC2,GATAD2B,MTERF,MTA1,PTRFB,GATAD2A,BRF1,PTRF |
| Mitochondrial transcription initiation | POLRMT |
| Mitochondrial Gene Expression | PPRC1,POLRMT,TFB1M,MTERFD1,PPARGC1B,ESRRA |
| Mitochondrial biogenesis | ESRRA,TFB1M,PPRC1,C10orf2,POLG2,POLRMT,GABPB1,PPARGC1B,GABPA,MTERF |
| Gene Expression | USP9X,ANP32A,GTF3AB,TSEN54,EED,DARS,ZNF599,ZNF689,ZNF664,DNMT3B |
| Energy Metabolism | PPARGC1B,TFB1M,ESRRA,UCP2,GABPA,MYBBP1A,MEF2B,UCP3 |
Protein Function
TFB2M has several biochemical functions, for example, poly(A) RNA binding,rRNA (adenine-N6,N6-)-dimethyltransferase activity,transcription cofactor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TFB2M itself. We selected most functions TFB2M had, and list some proteins which have the same functions with TFB2M. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| rRNA (adenine-N6,N6-)-dimethyltransferase activity | TFB1M,DIMT1L,METTL7B,METTL23,FAM86,DIMT1,PRDM13,METTL8,RRNAD1,NDUFAF5 |
| transcription cofactor activity | LDB1B,IRF3,NSD1,HES6,NFE2L1,MED30,TAF13,THRAP3,MED1,TFDP2 |
| poly(A) RNA binding | HNRNPAB,ZCCHC3,EIF2S1B,MECP2,DHX35,DHX8,DROSHA,UTP18,TRMT6,DIAP1 |
Interacting Protein
TFB2M has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFB2M here. Most of them are supplied by our site. Hope this information will be useful for your research of TFB2M.
TFAM;PHLDA3;ssrna_ug;C1qbp;Nek2;TUBG1;RAB4B;Ppp2ca;Gpkow;Cep131;Nup188;Tnpo1;Samm50;GAR1
Resources
Related Services
Related Products
References
- Bao, L; Cai, XX; et al. Grape seed procyanidin B2 ameliorates mitochondrial dysfunction and inhibits apoptosis via the AMP-activated protein kinase-silent mating type information regulation 2 homologue 1-PPAR gamma co-activator-1 alpha axis in rat mesangial cells under high-dose glucosamine. BRITISH JOURNAL OF NUTRITION 113:35-44(2015).
- Hayashi, G; Shen, Y; et al. Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia. HUMAN MOLECULAR GENETICS 23:6838-6847(2014).
