STX2
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Official Full Name
syntaxin 2 -
Overview
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
STX2;syntaxin 2;EPIM, epimorphin , STX2A, STX2B, STX2C;syntaxin-2;EPM;EPIM;Epimorphin;MGC51014;OTTHUMP00000238636;OTTHUMP00000238637;STX2_HUMAN;STX2A;STX2B;STX2C;Syntaxin 2C
Recombinant Proteins
- Mouse
- Human
- Chicken
- Rat
- E.coli
- Wheat Germ
- Mammalian Cell
- E.coli expression system
- HEK293T
- HEK293
- In Vitro Cell Free System
- Non
- His
- GST
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Stx2-411M |
Active Recombinant Mouse Syntaxin 2
|
E.coli | Mouse | Non | 1-189 a.a. |
|
| STX2-30658TH | Recombinant Human STX2 | Wheat Germ | Human | Non | 287 amino acids |
|
| STX2-3547C | Recombinant Chicken STX2 | Mammalian Cell | Chicken | His |
|
|
| STX2-4046H | Recombinant Human STX2 Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| STX2-5813R | Recombinant Rat STX2 Protein | Mammalian Cell | Rat | His |
|
|
| STX2-6854H | Recombinant Human Syntaxin 2, His-tagged | E.coli | Human | His | 1-264aa |
|
| STX2-1718HCL | Recombinant Human STX2 cell lysate | Human | Non |
|
||
| RFL15805HF | Recombinant Full Length Human Syntaxin-2(Stx2) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-288) |
|
| RFL20799RF | Recombinant Full Length Rat Syntaxin-2(Stx2) Protein, His-Tagged | E.coli expression system | Rat | His | Full L. Full Length (1-290) |
|
| STX2-1546H | Recombinant Human STX2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
|
|
| STX2-2990H | Recombinant Human STX2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
|
|
| STX2-4748HF | Recombinant Full Length Human STX2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 287 amino acids |
|
| STX2-512HF | Recombinant Full Length Human STX2 Protein | In Vitro Cell Free System | Human | Full L. 287 amino acids |
|
|
| STX2-5472R | Recombinant Rat STX2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| STX2-5472R-B | Recombinant Rat STX2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
||
| STX2-5749H | Recombinant Human STX2 Protein (Met1-Arg188), N-His tagged | E.coli | Human | His | Met1-Arg188 |
|
| Stx2-961M | Recombinant Mouse Stx2 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
Involved Pathway
STX2 involved in several pathways and played different roles in them. We selected most pathways STX2 participated on our site, such as SNARE interactions in vesicular transport,Synaptic vesicle cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with STX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SNARE interactions in vesicular transport | BNIP1,GOSR2,STX1A,VTI1A,USE1,STX5A,STX8,VAMP3,STX19,VAMP7 |
| Synaptic vesicle cycle | SLC18A2,ATP6V0E2,VAMP2,UNC13C,CPLX3,CPLX2,NSF,ATP6V1A,STXBP1,ATP6V1D |
Protein Function
STX2 has several biochemical functions, for example, SNAP receptor activity,SNARE binding,calcium-dependent protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STX2 itself. We selected most functions STX2 had, and list some proteins which have the same functions with STX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SNAP receptor activity | SNAP25,STX6,STX4,VTI1B,SEC22A,STX18,VAMP5,VAMP8,STX2A,SNAP23.1 |
| protein binding | MOB3C,VIPR1,MAPK12,KRTAP23-1,POLDIP2,SEPT9,AHSA2,DNAJA2,CCNT1,ATP11C |
| protein dimerization activity | HER4.2,BETA3,MEF2CA,HIF1AB,TFAP2C,HER12,MESPAA,STAT5B,TCF21,NEUROG3 |
| calcium-dependent protein binding | CALM1,TSG101,S100A6,VAMP2,VLDLR,S100A1,S100B,CALM2,S100A4,MBL1 |
| SNARE binding | STX11A,TNFAIP2,SEC22BA,VAMP2,VAMP4,TNFAIP2A,VAMP3,STXBP1,EXOC3L4,STX1A |
Interacting Protein
STX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of STX2.
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References
- Diodati, ME; Bates, AH; et al. High Genotypic and Phenotypic Similarity Among Shiga Toxin-Producing Escherichia coli O111 Environmental and Outbreak Strains. FOODBORNE PATHOGENS AND DISEASE 12:235-243(2015).
- Arimitsu, H; Sasaki, K; et al. Isolation of B subunit-specific monoclonal antibody clones that strongly neutralize the toxicity of Shiga toxin 2. MICROBIOLOGY AND IMMUNOLOGY 59:71-81(2015).
