SKA2
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Official Full Name
spindle and kinetochore associated complex subunit 2 -
Synonyms
SKA2;spindle and kinetochore associated complex subunit 2;FAM33A, family with sequence similarity 33, member A;spindle and kinetochore-associated protein 2;FLJ12758;FAM33A;Family with sequence similarity 33, member A;MGC110975;Protein FAM33A;SKA 2;SKA2_HUMAN;Spindle and kinetochore associated protein 2;Spindle and KT (kinetochore) associated 2;Spindle and KT associated 2
Recombinant Proteins
- Mouse
- Human
- Rhesus macaque
- Rat
- Cynomolgus
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- His&T7
- GST
- His&Fc&Avi
Involved Pathway
SKA2 involved in several pathways and played different roles in them. We selected most pathways SKA2 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with SKA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RHO GTPase Effectors | KNTC1,PRC1B,MKL1,SPC25,SKA1,MKL1B,NUF2,WASF3,CIT,FMNL1 |
| M Phase | SET,AHCTF1,NCAPH,ENSAA,SGOL1,CENPN,RCC2,NCAPD2,TMEM188,NEK7 |
| Mitotic Metaphase and Anaphase | ANKLE2,ZWINT,NUF2,PDS5B,CENPH,NDEL1A,RANGAP1B,ZW10,MIS12,TMPO |
| Mitotic Prometaphase | INCENP,NUF2,DSN1,NDEL1B,CENPI,PDS5B,CLIP1,B9D2,ZWINT,RCC2 |
| RHO GTPases Activate Formins | EVL,SKA1,NSL1,KNTC1,PMF1,RANGAP1B,NUF2,RHOAE,AHCTF1,DIAPH1 |
| Cell cycle | CDKN1B,GORASP1,NINL,CDC25C,GINS2,DCTN3,TMPO,CCNE2,CEP164,MCM3L |
| Cell Cycle, Mitotic | ZWILCH,DNA2,STAG1,CTDNEP1,CEP76,NINL,NIPBLA,NCAPG,LIN54,KIF2C |
| Mitotic Anaphase | TMPO,ZWINT,CENPQ,LEMD3,RANGAP1B,CENPL,ZWILCH,B9D2,CENPO,CENPE |
Protein Function
SKA2 has several biochemical functions, for example, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SKA2 itself. We selected most functions SKA2 had, and list some proteins which have the same functions with SKA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| microtubule binding | VAPA,AKAP1,DYNC1I1,GAS2L2,HDAC6,MTAP4,PAFAH1B1A,LC3,KIF3C,HOOK3 |
Interacting Protein
SKA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SKA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SKA2.
Hmga2
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References
- Rice, L; Waters, CE; et al. Identification and functional analysis of SKA2 interaction with the glucocorticoid receptor. JOURNAL OF ENDOCRINOLOGY 198:499-509(2008).
- TEWODROS, W; NORGREN, M; et al. STREPTOKINASE ACTIVITY AMONG GROUP-A STREPTOCOCCI IN RELATION TO STREPTOKINASE GENOTYPE, PLASMINOGEN BINDING, AND DISEASE MANIFESTATIONS. MICROBIAL PATHOGENESIS 18:53-65(1995).
