SETMAR
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Official Full Name
SET domain and mariner transposase fusion gene -
Overview
Histone-lysine N-methyltransferase SETMAR is an enzyme that in humans is encoded by the SETMAR gene. -
Synonyms
SETMAR;SET domain and mariner transposase fusion gene;histone-lysine N-methyltransferase SETMAR;metnase;Histone lysine N methyltransferase SETMAR;Hsmar 1;Hsmar1;Mariner transposase Hsmar1;SET domain and mariner transposase fusion;SET domain and mariner transposase fusion gene containing protein;SET domain and mariner transposase fusion gene-containing protein;SETMR_HUMAN
Recombinant Proteins
- Mouse
- Rat
- Zebrafish
- Human
- Mammalian Cells
- Sf9 Cells
- E.coli
- HEK293
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SETMAR involved in several pathways and played different roles in them. We selected most pathways SETMAR participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SETMAR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysine degradation | SUV39H1,WHSC1,AADAT,SETDB1B,PLOD3,SETD1B,DLST,ALDH9A1A.1,MLL1,GCDH |
Protein Function
SETMAR has several biochemical functions, for example, DNA topoisomerase binding,double-stranded DNA binding,endonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SETMAR itself. We selected most functions SETMAR had, and list some proteins which have the same functions with SETMAR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| single-stranded DNA endodeoxyribonuclease activity | RBBP8,DCLRE1C,ERCC4,MRE11A |
| structure-specific DNA binding | EXO1,TET1,TDG,ENDOV |
| histone methyltransferase activity (H3-K4 specific) | ASH1L,KMT2A,WBP7,WHSC1L1,WDR82,SMYD1B,MLL5,MLL1,SETD3,KMT2E |
| endonuclease activity | G3BP1,DCLRE1C,MRE11A,RNASEKA,FEN1,PNKP,RNASEL2,RAG1,EME2,RNASE6 |
| zinc ion binding | RNF145B,EHMT2,CHORDC1,RFPL1,PIAS4A,C6AST4,PGLYRP1,ZNRF3,APOBEC2,LIN28A |
| histone methyltransferase activity (H3-K36 specific) | SMYD2A,SETD2,NSD1,ASH1L,SMYD2B,SETD3,SMYD2 |
| protein homodimerization activity | CD2,DMRT1,CTBP2,GPD1,ACAT1,GDF6,QPRT,UGT1A2,UGT1A3,S100A11 |
| DNA topoisomerase binding | TOPORS |
| single-stranded DNA binding | HNRNPDL,RAD51,LUZP4,RPA4,BRCA2,XRCC2,XRCC3,RAD51AP1,FBXO18,PURB |
Interacting Protein
SETMAR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SETMAR here. Most of them are supplied by our site. Hope this information will be useful for your research of SETMAR.
H3F3C;Naa50;LEO1
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