RIN2
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Official Full Name
RAB5 interacting protein 2 -
Overview
The RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP-bound form of the RAB5 protein preferentially over the GDP-bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia cutis laxa and scoliosis (MACS) syndrome, an elastic tissue disorder, as well as the related connective tissue disorder, RIN2 syndrome. Alternative splicing results in multiple transcript variants. -
Synonyms
RIN2;RAB5 interacting protein 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RIN2-722H | Recombinant Human RIN2 Protein, GST-tagged | E.coli | Human | GST | 785-879 a.a. |
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| RFL19022AF | Recombinant Full Length Arabidopsis Thaliana E3 Ubiquitin Protein Ligase Rin2(Rin2) Protein, His-Tagged | E.coli | Arabidopsis thaliana | His | Full L. Full Length (1-578) |
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| RIN2-1040H | Recombinant Human RIN2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| RIN2-1347H | Recombinant Human RIN2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Rin2-5517M | Recombinant Mouse Rin2 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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Involved Pathway
RIN2 involved in several pathways and played different roles in them. We selected most pathways RIN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RIN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
RIN2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by RIN2 itself. We selected most functions RIN2 had, and list some proteins which have the same functions with RIN2. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
RIN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RIN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RIN2.
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