RFX3

  • Official Full Name

    regulatory factor X, 3 (influences HLA class II expression)

  • Overview

    This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.

  • Synonyms

    RFX3;regulatory factor X, 3 (influences HLA class II expression);transcription factor RFX3;DNA binding protein RFX3;Regulatory factor X 3;RFX3_HUMAN;OTTHUMP00000020993;OTTHUMP00000020994;bA32F11.1

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • Mammalian Cell
  • HEK293
  • HEK293T
  • Mammalian cells
  • His
  • Non
  • Myc&DDK
  • Flag
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
RFX3-2265H Recombinant Human RFX3, His-tagged E.coli Human His 1-413aa
RFX3-14114M Recombinant Mouse RFX3 Protein Mammalian Cell Mouse His
RFX3-4990Z Recombinant Zebrafish RFX3 Mammalian Cell Zebrafish His
RFX3-2398HCL Recombinant Human RFX3 293 Cell Lysate HEK293 Human Non
RFX3-1021H Recombinant Human RFX3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
RFX3-1622HFL Recombinant Full Length Human RFX3 Protein, C-Flag-tagged Mammalian cells Human Flag Full L.
RFX3-1886H Recombinant Human RFX3 Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
RFX3-1886H-B Recombinant Human RFX3 Protein Pre-coupled Magnetic Beads HEK293 Human
Rfx3-5481M Recombinant Mouse Rfx3 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
RFX3-7551M Recombinant Mouse RFX3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
RFX3-7551M-B Recombinant Mouse RFX3 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    RFX3 involved in several pathways and played different roles in them. We selected most pathways RFX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RFX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    RFX3 has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RFX3 itself. We selected most functions RFX3 had, and list some proteins which have the same functions with RFX3. You can find most of the proteins on our site.

    Function Related Protein
    transcription regulatory region DNA binding ZNF217,RNF10,REST,SNCA,TBP,SOX17,HNRNPL,BCL11B,GATA6,FOXI1
    transcription factor activity, sequence-specific DNA binding TAF1B,OTX1B,FOXG1D,ENO1,ZNF134,MNX2A,ELK4,ETV6,FOXO4,PBX1
    protein binding CSPG5,LRRC25,TACSTD2,FOXB1,NRBF2,GFER,KDR,ODF1,HSPA12B,KBTBD7
    RNA polymerase II core promoter proximal region sequence-specific DNA binding MEF2A,ELF3,MAFB,CTCFL,TCF3A,KLF16,PITX1,TFAP2E,TBX20,RBPJA
    DNA binding ZBTB12,MSXE,ZFP518A,SETDB1B,SPRTN,POU2AF1,TBX16,ONECUT3,HIST1H4B,HOXA4
    transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding PAX3,FOXC2,MYF5,HNF1B,ATF2,NKX2,NR5A1,HIF1A,MITF,LEF1

    Interacting Protein

    RFX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RFX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RFX3.

    FHL2;FHL3;TRIP6;TRAF2;RFX6

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