RANGRF
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Official Full Name
RAN guanine nucleotide release factor -
Overview
This gene encodes a protein that has been shown to function as a guanine nucleotide release factor in mouse and to regulate the expression and function of the Nav1.5 cardiac sodium channel in human. Alternative splicing results in multiple transcript variants. -
Synonyms
RANGRF;RAN guanine nucleotide release factor;HSPC165;HSPC236;MOG1;MOG1 homolog (S. cerevisiae);RANGNRF;homolog of yeast MOG1;likely ortholog of mouse RAN guanine nucleotide release factor;MOG 1;MOG1 homolog;ran-binding protein MOG1
Recombinant Proteins
- Mouse
- Rhesus macaque
- Zebrafish
- Human
- Mammalian Cells
- E.coli
- HEK293
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
RANGRF involved in several pathways and played different roles in them. We selected most pathways RANGRF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RANGRF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RANGRF has several biochemical functions, for example, Ran GTPase binding,Ran guanyl-nucleotide exchange factor activity,guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RANGRF itself. We selected most functions RANGRF had, and list some proteins which have the same functions with RANGRF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Ran guanyl-nucleotide exchange factor activity | ALS2,RANBP10,SERGEF,RCBTB2,RCC1 |
| Ran GTPase binding | XPO7,RANBP2,XPOT,IPO4,RANBP3,RANGAP1,NUP153,IPO13,XPO4,RANBP10 |
| sodium channel regulator activity | PTPN3,AGT,SCN1BB,SCLT1,GPD1L,SCN3B,NOS1,PKP2,SGK3,FGF12 |
| ion channel binding | PKD1,HTT,PKD2,CALM,AASS,DIAPH1,S100A10,ARRB1,YWHAE,PDE4D |
| guanyl-nucleotide exchange factor activity | TRIOA,FGD1,DENND6A,DOCK5,RALGPS2,GDPGP1,VAV2,GCGR,RAPGEF6,P2RY12 |
| protein transporter activity | ARFGAP3,RAMP3,TIMM9,TMCO6,VPS26BL,IPO7,CALCRL,RAP1A,AP3S1,COX18 |
Interacting Protein
RANGRF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RANGRF here. Most of them are supplied by our site. Hope this information will be useful for your research of RANGRF.
Ranbp2
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