RALB
-
Official Full Name
v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) -
Overview
RalA and RalB are members of the Ras family of small GTPases and are highly homologous in protein sequence. The functions of RalA and RalB are distinct yet overlapping. By binding to various effector proteins, RalA and RalB serve as important GTP sensors -
Synonyms
RALB;v-ral simian leukemia viral oncogene homolog B (ras related;GTP binding protein);ras-related protein Ral-B;RAS-like protein B;GTP binding protein
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
RALB involved in several pathways and played different roles in them. We selected most pathways RALB participated on our site, such as Ras signaling pathway,Rap signaling pathway,Phospholipase D signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RALB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pathways in cancer | GSTP1,XIAP,FGFR3,RASSF1,FGF14,VEGFC,ITGA6,FLT3,CCNA1,RARA |
| Phospholipase D signaling pathway | AVPR2,GRM1,PIK3CB,INS2,MAPK1,PIK3R5,RRAS,KRAS,PDGFC,PTGFR |
| Rap signaling pathway | BRAF,FGFR3,PLCB2,DOCK4,RAPGEF1,ARAP3,CDH1,CALM4,RAP1A,FGF17 |
| Ras signaling pathway | INS1,FGF22,RAB5B,IKBKB,MAPK1,PLA2G2D,SHC1,INS,RGL2,PLA2G2F |
| Pancreatic cancer | PIK3R5,TP53,ARHGEF6,TRP53,IKBKG,SMAD4,AKT2,BRCA2,BRAF,AKT1 |
Protein Function
RALB has several biochemical functions, for example, ATPase binding,GDP binding,GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RALB itself. We selected most functions RALB had, and list some proteins which have the same functions with RALB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | GNA15.1,RAB40AL,ARFRP1,GNAT3,ARF3,ADSSL1,TUBB1,RAB25,MFN1B,SCG5 |
| protein binding | TIMM8A,S100A10,ACYP2,SYTL2,CA8,RPS3A,HOOK3,TBC1D14,EIF4ENIF1,MCM2 |
| GDP binding | RAP2C,SRP54,SRP54A,RAB10,RAB27B,RHOA,RAB5B,RAB2A,PRPS1,GNAI1 |
| ATPase binding | RAB4A,TOR1AIP1,NSFL1C,ATP6V0A1A,NUFIP1,SELS,NKAIN1,DRD1A,GABARAPL2,SVIP |
| ubiquitin protein ligase binding | AURKA,H2-AB1,HSPD1,OTUB1,CUL3,PA2G4,UCHL1,CALR,MAP1LC3C,SUMO1 |
| GTPase activity | RAB2B,RAB39B,EIF5B,GFM1,RAB10,GNAV1,DNM3,RAB28,ARL8B,GNG3 |
Interacting Protein
RALB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RALB here. Most of them are supplied by our site. Hope this information will be useful for your research of RALB.
CALM1;Ccnd1;Ralbp1;RALBP1;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;pi3p;Exoc2;ATG12;ATP6V1A;Flnb;ATG5;Coro1c;Gabarapl1;BECN1;Exoc3;Atg5
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