PYCR2
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Official Full Name
pyrroline-5-carboxylate reductase family, member 2 -
Overview
Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. -
Synonyms
PYCR2;pyrroline-5-carboxylate reductase family, member 2;pyrroline-5-carboxylate reductase 2;P5CR2;Leftb;1810018M05Rik;FLJ54750;OTTHUMP00000035614;P5C reductase 2;P5CR 2;P5CR2_HUMAN;PYCR 2;Pyrroline 5 carboxylate reductase 2;Pyrroline 5 carboxylate reductase family member 2;Pyrroline 5 carboxylate reductase isoform;RP4-559A3.4;pyrroline 5-carboxylate reductase isoform
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Mammalian cells
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
PYCR2 involved in several pathways and played different roles in them. We selected most pathways PYCR2 participated on our site, such as Arginine and proline metabolism,Metabolic pathways,Biosynthesis of amino acids, which may be useful for your reference. Also, other proteins which involved in the same pathway with PYCR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Biosynthesis of amino acids | ACO2,ENO3,MAT2A,BCAT2,TPI1,TKTL2,ALDOB,TKT,THA1,PKM |
| Arginine and proline metabolism | GOT2,P4HA3,DAO.1,P4HA1,NOS3,LSM1,L3HYPDH,AZIN2,ALDH3A2,PYCR1B |
| Metabolic pathways | TGDS,HPDA,PCCA,DHODH,UQCRQ,PLCD3,KLF15,PPAP2A,ATP5I,SEPHS2 |
Protein Function
PYCR2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PYCR2 itself. We selected most functions PYCR2 had, and list some proteins which have the same functions with PYCR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
PYCR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PYCR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PYCR2.
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