POMGNT1
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Official Full Name
protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase -
Overview
The protein encoded by this gene is a type II transmembrane protein that resides in the golgi. It participates in O-mannosyl glycosylation, and is specific for alpha linked terminal mannose. Mutations in this gene are associated with muscle-eye-brain (MEB) disease. Alternatively spliced transcript variants have been found for this gene. -
Synonyms
POMGNT1;protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase;protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1;FLJ20277;MGAT1.2;protein O mannose beta 1;2 N acetylglucosaminyltransferase;UDP-GlcNAc:alpha-D-mannoside be
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rat
- Sf21 Cells
- Mammalian Cells
- HEK293
- E.coli
- His
- His&Fc&Avi
Involved Pathway
POMGNT1 involved in several pathways and played different roles in them. We selected most pathways POMGNT1 participated on our site, such as Other types of O-glycan biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with POMGNT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Other types of O-glycan biosynthesis | B4GALT2,CHST10,POFUT1,B3GALTL,POGLUT1,ST6GAL2,C3orf64,COLGALT2,OGT.1,GXYLT2 |
Protein Function
POMGNT1 has several biochemical functions, for example, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POMGNT1 itself. We selected most functions POMGNT1 had, and list some proteins which have the same functions with POMGNT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ECH1,GORASP1,LRRC29,C5orf30,HSPA1B,CORO6,PHF7,BRD9,SYNDIG1,B2M |
| beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity | B3GNT3,B3GNT6 |
Interacting Protein
POMGNT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POMGNT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POMGNT1.
LNX1;CXCL8;SOX6;BRCA1;ZBTB18;SLC38A1
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