POLR2J3
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Official Full Name
polymerase (RNA) II (DNA directed) polypeptide J3 -
Overview
DNA-directed RNA polymerase II subunit RPB11-b2, also known as POLR2J3, belongs to the eukaryotic RPB11 RNA polymerase subunit family. POLR2J (DNA-directed RNA polymerase II subunit J) exist as three variants POLR2J1 (RPB11-a), POLR2J2 (RPB11-b1), and POLR2J3 (RPB11-b2). POLR2J3 is DNA-dependent RNA polymerases that catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. -
Synonyms
POLR2J2;RPB11b1;RPB11b2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POLR2J3-7175H | Recombinant Human POLR2J3 polymerase (RNA) II (DNA directed) polypeptide J3, His-tagged | E.coli | Human | His | 1-115aa |
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| POLR2J3-2453H | Recombinant Human POLR2J3 Protein, MYC/DDK-tagged | HEK293 | Human | DDK&Myc |
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| POLR2J3-5216H | Recombinant Human POLR2J3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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Involved Pathway
POLR2J3 involved in several pathways and played different roles in them. We selected most pathways POLR2J3 participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR2J3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA polymerase | POLR1C,POLR2J2,POLR3A,POLR2EB,POLR1A,POLR1B,POLR3E,POLR2K,POLR2J,POLR2G |
| Metabolic pathways | NDUFA12,PIGM,CYP2C39,ACAA1A,ASAH1,PFKMA,TH,GATB,CYP2A12,MUT |
| Purine metabolism | POLE,ADSSL1,POLA1,POLR3G,AMPD1,PDE11A,NME6,GMPR,NT5C,URAH |
| Huntingtons disease | NDUFA2,PLCB4,DNAI2,DNAHC8,GRIN1,NDUFC2,TBPL1,DCTN4,NDUFA4,TGM2 |
| Pyrimidine metabolism | ITPA,NT5C1B-RDH14,POLR3D,UPB1,TK1,POLR2E,DCTPP1,UCK2,CTPS1A,udp |
| Epstein-Barr virus infection | PSMC5,TRAF3,HLA-DRA,GTF2B,CCNA1,HSPA6,ENTPD1,GTF2E2,SND1,IKBKG |
Protein Function
POLR2J3 has several biochemical functions, for example, DNA binding,contributes_to RNA polymerase II activity,protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR2J3 itself. We selected most functions POLR2J3 had, and list some proteins which have the same functions with POLR2J3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein dimerization activity | LMLN,EBF3A,TCF15,NLGN1,FBXW11,TFAP2C,PRDX5,TWIST2,BETA3,MYCB |
| DNA binding | CTC1,HIF3A,HLTF,THAP5,PDS5B,KLF12,PURBB,ZNF16,HIST1H4F,HIST1H2BK |
| contributes_to RNA polymerase II activity | POLR2EB,POLR2A,POLR2F,POLR2B,POLR2H,POLR2E,POLR2C,POLR2J2,POLR2L,POLR2J |
Interacting Protein
POLR2J3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR2J3 here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR2J3.
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