PISD
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Official Full Name
phosphatidylserine decarboxylase -
Overview
Phosphatidylserine decarboxylases (PSDs; EC 4.1.1.65) catalyze the formation of phosphatidylethanolamine (PE) by;decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial;membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an;autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits (Schuiki and Daum, 2009;(PubMed 19165886)). -
Synonyms
PISD;phosphatidylserine decarboxylase;phosphatidylserine decarboxylase proenzyme;dJ858B16.2;PSDC;PSD;PSSC;DJ858B16;DKFZp566G2246
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Wheat Germ
- Insect Cells
- Mammalian Cells
- In Vitro Cell Free System
- GST
- His
- His&SUMO
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PISD-1731H | Recombinant Human PISD, GST-tagged | E.coli | Human | GST | 1-375aa | |
| PISD-15H | Recombinant Human PISD protein, GST-tagged | Wheat Germ | Human | GST | 1-409 a.a. |
|
| PISD-16H | Recombinant Human PISD protein, GST-tagged | Wheat Germ | Human | GST | 62-170 a.a. |
|
| PISD-17H | Recombinant Human PISD protein, His-tagged | Insect Cells | Human | His | 1-375 a.a. |
|
| PISD-4892Z | Recombinant Zebrafish PISD | Mammalian Cells | Zebrafish | His |
|
|
| PISD-001H | Recombinant Human PISD Protein, His-tagged | E.coli | Human | His | Full L. |
|
| PISD-18H | Recombinant Human PISD Protein, His/SUMO-tagged | E.coli | Human | His&SUMO | 1-375aa |
|
| Pisd-1940M | Recombinant Mouse Pisd Protein, His-tagged | E.coli | Mouse | His | Met1-Leu406 |
|
| PISD-625HF | Recombinant Full Length Human PISD Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 409 amino acids |
|
Involved Pathway
PISD involved in several pathways and played different roles in them. We selected most pathways PISD participated on our site, such as Glycerophospholipid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PISD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycerophospholipid metabolism | CHATA,PTDSS2,PTDSS1A,CDS2,PCYT1A,PLA2G2D,PCYT1AB,DGKB,LPIN1,PLA2G5 |
| Metabolic pathways | POLA1,IDH3G,DNMT1,ALG14,MLYCD,POLR1C,B3GALNT1,CYP2C54,NAPRT,ATP5G3 |
Protein Function
PISD has several biochemical functions, for example, phosphatidylserine decarboxylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PISD itself. We selected most functions PISD had, and list some proteins which have the same functions with PISD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylserine decarboxylase activity | GOT1 |
Interacting Protein
PISD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PISD here. Most of them are supplied by our site. Hope this information will be useful for your research of PISD.
DHX29;DAGLB
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References
- Pierucci, D; Cicconi, S; et al. NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro. DIABETOLOGIA 44:1281-1295(2001).
- Dowhan, W; et al. A retrospective: Use of Escherichia coli as a vehicle to study phospholipid synthesis and function. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 1831:471-494(2013).
